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首页> 外文期刊>Environmental Science & Technology >Exposure of Nail Salon Workers to Phthalates, Di(2-ethylhexyl) Terephthalate, and Organophosphate Esters: A Pilot Study
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Exposure of Nail Salon Workers to Phthalates, Di(2-ethylhexyl) Terephthalate, and Organophosphate Esters: A Pilot Study

机译:指甲沙龙工人接触邻苯二甲酸盐,对苯二甲酸二(2-乙基己基)酯和有机磷酸酯的暴露:一项初步研究

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Relatively little is known about the exposure of nail technicians to semivolatile organic compounds (SVOCs) in nail salons. We collected preshift and postshift urine samples and silicone wrist bands (SWBs) worn on lapels and wrists from 10 female nail technicians in the Boston area in 2016-17. We analyzed samples for phthalates, phthalate alternatives, and organophosphate esters (OPEs) or their metabolites. Postshift urine concentrations were generally higher than preshift concentrations for SVOC metabolites; the greatest change was for a metabolite of the phthalate alternative di(2-ethylhexyl) terephthalate (DEHTP): mono(2-ethyl-5-carboxypentyl) terephthalate (MECPTP) more than tripled from 11.7 to 36.6 mu g/g creatinine. DEHTP biomarkers were higher in our study participants postshift urine compared to 2015-2016 National Health and Nutrition Examination Survey females. Urinary MECPTP and another DEHTP metabolite were moderately correlated (r = 0.37-0.60) with DEHTP on the SWBs, suggesting occupation as a source of exposure. Our results suggest that nail technicians are occupationally exposed to certain phthalates, phthalate alternatives, and OPEs, with metabolites of DEHTP showing the largest increase across a work day. The detection of several of these SVOCs on SWBs suggests that they can be used as a tool for examining potential occupational exposures to SVOCs among nail salon workers.
机译:关于指甲技术员在指甲沙龙中暴露于半挥发性有机化合物(SVOC)的了解相对较少。我们收集了2016-17年度波士顿地区10名女性指甲技术员在翻领和手腕上佩戴的移位前和移位后尿液样本以及硅胶腕带(SWB)。我们分析了样品中的邻苯二甲酸盐,邻苯二甲酸盐替代品和有机磷酸酯(OPE)或其代谢产物。移位后的尿液浓度通常高于移位前的SVOC代谢物浓度;最大的变化是邻苯二甲酸酯对苯二甲酸二(2-乙基己基)酯(DEHTP)的代谢产物:对苯二甲酸单(2-乙基-5-羧基戊基)对苯二甲酸酯(MECPTP)从11.7μg/ g肌酐增加了两倍多。相较于2015-2016年美国国家健康与营养检查调查(National Health and Nutrition Examination Survey)雌性,我们的研究参与者移位后尿液中的DEHTP生物标志物更高。尿中的MECPTP和另一种DEHTP代谢产物与SWB上的DEHTP有中等程度的相关性(r = 0.37-0.60),表明职业是暴露的来源。我们的结果表明,指甲技术人员在职业上会接触某些邻苯二甲酸盐,邻苯二甲酸盐替代品和OPE,而DEHTP的代谢产物在整个工作日中表现出最大的增长。对SWB上的几种SVOC的检测表明,它们可以用作检查美甲沙龙工人潜在的SVOC职业暴露的工具。

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