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Respirable Particulate Constituents and Risk of Cause-Specific Mortality in the Hong Kong Population

机译：香港人口的可吸入颗粒物成分和特定原因致死的风险

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摘要

Emerging studies examined the associations of particulate matter constituents with nonaccidental and cardiorespiratory diseases, but few have investigated more specific causes of cardiorespiratory diseases or other system diseases, especially in Asia. We estimated the association between respirable particulate matter (PM10) constituents and a spectrum of deaths using a quasi-Poisson time-series model in Hong Kong. Positive associations were identified between cause specific deaths and elemental carbon, organic carbon (OC), nitrate, and potassium ion (K+), but only the associations for OC and K+ were robust in the two-constituent models adjusting for other constituents. The estimated effects of OC were strongest on mortality from the respiratory system with cumulative percent excess risk (ER%) of 3.82% (95% CI: 0.96%, 6.92%) per interquartile range (6.7 mu g/m(3)) increase over 7 days prior to death (lag(0-7)), especially for pneumonia (ER%: 4.32%; 95% CI: 0.70%, 8.26%). The digestive system was most sensitive to with cumulative ER% of 6.74% (95% CI: 0.37%, 14.01%) per interquartile range (0.6 mu g/m(3)) increase. This study indicates that PM10 constituents from biomass burning (OC and K+) were more toxic than other constituents for deaths in Hong Kong, especially for mortalities from respiratory and digestive systems. These findings should have potential biological and pollution control implications.
机译：新兴研究检查了颗粒物成分与非偶然性和心肺疾病的关联，但很少有人研究更具体的心肺疾病或其他系统疾病的病因，尤其是在亚洲。我们使用拟泊松时间序列模型在香港估算了可吸入颗粒物（PM10）成分与一系列死亡之间的关联。在特定原因死亡与元素碳，有机碳（OC），硝酸盐和钾离子（K +）之间鉴定出正关联，但是在针对其他成分进行调整的两成分模型中，只有OC和K +关联强。 OC估计对呼吸系统死亡率的影响最强，每四分位间距（6.7μg / m（3））增加的累积超额风险百分比（ER％）为3.82％（95％CI：0.96％，6.92％）死亡前7天（滞后（0-7）），尤其是对于肺炎（ER％：4.32％； 95％CI：0.70％，8.26％）。消化系统最敏感，每四分位间距（0.6μg / m（3））增加时，累积ER％为6.74％（95％CI：0.37％，14.01％）。这项研究表明，生物质燃烧产生的PM10成分（OC和K +）对香港的死亡比其他成分更具毒性，尤其是对于呼吸系统和消化系统的死亡。这些发现应具有潜在的生物和污染控制意义。

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  • 来源
    《Environmental Science & Technology》 |2019年第16期|9810-9817|共8页
  • 作者

    Sun Shengzhi; Cao Wangnan; Pun Vivian C.; Qiu Hong; Ge Yang; Tian Linwei;

  • 作者单位

    Univ Hong Kong Sch Publ Hlth Hong Kong Peoples R China|Brown Univ Dept Epidemiol Sch Publ Hlth Providence RI 02912 USA;

    Brown Univ Ctr Evidence Synth Hlth Sch Publ Hlth Providence RI 02912 USA;

    Chinese Univ Hong Kong Jockey Club Sch Publ Hlth & Primary Care Hong Kong Peoples R China;

    Univ Hong Kong Sch Publ Hlth Hong Kong Peoples R China;

    Univ Georgia Sch Publ Hlth Dept Epidemiol & Biostat Athens GA 30606 USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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