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首页> 外文期刊>Environmental Science & Technology >Association between Serum Polybrominated Diphenyl Ether Levels and Residential Proximity to Solid-Waste Facilities
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Association between Serum Polybrominated Diphenyl Ether Levels and Residential Proximity to Solid-Waste Facilities

机译：血清多溴联苯醚水平与居民对固体废物设施的接近程度之间的关联

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摘要

As consumer products treated with polybrominated diphenyl ethers (PBDEs) reach the end of their life cycle, they often are discarded into solid-waste facilities, offering a potential reservoir for exposure. The likelihood of exposures to PBDEs by residents living near those sites rarely has been explored. This study collected blood samples from 923 female participants in the California Teachers Study in 2011-2013 and examined the association between participants' residential proximity to solid-waste facilities with potential release of PBDEs and serum levels of three congeners (BDE-47, BDE-100, and BDE-153). General linear regression analysis was used to examine the association, adjusting for age, race, body-mass index, neighborhood socioeconomic status, and urban residency. Compared to participants living ＞10 km from any selected site, those living within 2 km had 45% higher BDE-47 (95% CI: 5-100%) and BDE-100 (95% CI: 0-109%) levels, and those living between 2 and 10 km had 35% higher BDE-47 (95% CI: 0-82%) and 29% higher BDE-100 (95% CI: -9 to 82%) levels. No associations were found for BDE-153. Living close to some solid waste sites may be related to higher serum BDE-47 and BDE-100 levels. Studies with comprehensive exposure assessments are needed to confirm these initial observations.
机译：用多溴二苯醚（PBDEs）处理的消费品达到其生命周期的尽头时，通常会将它们丢弃到固体废物处理设施中，从而为暴露提供了潜在的资源库。很少探索住在这些地点附近的居民接触多溴二苯醚的可能性。这项研究从2011年至2013年的加利福尼亚教师研究中从923名女性参与者中收集了血液样本，并研究了参与者居住在固体废物设施附近与PBDEs可能释放与三种同类物的血清水平之间的关系（BDE-47，BDE- 100和BDE-153）。使用一般线性回归分析来检查该关联，并调整年龄，种族，身体质量指数，邻里社会经济地位和城市居民身份。与居住在任何选定地点＞ 10 km的参与者相比，居住在2 km以内的参与者的BDE-47（95％CI：5-100％）和BDE-100（95％CI：0-109％）的水平高45％，而居住在2至10公里之间的人的BDE-47水平升高了35％（95％CI：0-82％），而BDE-100的水平升高了29％（95％CI：-9至82％）。找不到与BDE-153的关联。生活在一些固体废物场所附近可能与血清BDE-47和BDE-100的升高有关。需要进行全面的暴露评估研究以确认这些初步观察结果。

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  • 来源
    《Environmental Science & Technology》 |2016年第7期|3945-3953|共9页
  • 作者

    Ruiling Liu; David O. Nelson; Susan Hurley; Myrto Petreas; June-Soo Park; Yunzhu Wang; Weihong Guo; Leslie Bernstein; Andrew Hertz; Peggy Reynolds;

  • 作者单位

    Cancer Prevention Institute of California, Berkeley, California 94704, United States;

    Cancer Prevention Institute of California, Berkeley, California 94704, United States;

    Cancer Prevention Institute of California, Berkeley, California 94704, United States;

    Department of Toxic Substances Control, California Environmental Protection Agency, Berkeley, California 95812, United States;

    Department of Toxic Substances Control, California Environmental Protection Agency, Berkeley, California 95812, United States;

    Department of Toxic Substances Control, California Environmental Protection Agency, Berkeley, California 95812, United States;

    Department of Toxic Substances Control, California Environmental Protection Agency, Berkeley, California 95812, United States;

    Department of Population Sciences, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States;

    Cancer Prevention Institute of California, Berkeley, California 94704, United States;

    Cancer Prevention Institute of California, Berkeley, California 94704, United States,Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California 94305, United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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