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首页> 外文期刊>Environmental Science & Technology >Portable Colorimetric Paper-Based Biosensing Device for the Assessment of Bisphenol A in Indoor Dust
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Portable Colorimetric Paper-Based Biosensing Device for the Assessment of Bisphenol A in Indoor Dust

机译：便携式比色纸基生物传感装置，用于评估室内粉尘中的双酚A

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摘要

Bisphenol A (BPA) is found in polycarbonate plastic and epoxy resins and is used in a variety of commercial and consumer products. The leaching of BPA can result in human exposure via inhalation, ingestion, and dermal routes. As a result, humans have been exposed in their home and work environment to BPA. Conventional methods for BPA exposure assessment rely on cumbersome laboratory instrumentation with high capital and operational expenditures which limit the number of samples that can be analyzed. We report here the design of a compact portable colorimetric paper-based biosensing device with integrated sampling/analysis units for field-based measurements of BPA in indoor dust. The system employs interchangeable low-cost paper-based enzyme sensors as a test zone for BPA detection interfaced with an air-sampling cassette as a sample collection area. The sensor response was concentration-dependent with a detection limit of 0.28μg/g. The sensor was validated with the conventional gas chromatography method and used to detect BPA exposure in household dust BPA concentrations ranged from 0.05 to 3.87μg/g in 57 household dust samples when both methods were used. The potential of this method for field measurements of dust samples is discussed.
机译：双酚A（BPA）存在于聚碳酸酯塑料和环氧树脂中，并用于各种商业和消费产品。 BPA的浸出可通过吸入，食入和皮肤途径导致人体暴露。结果，人类在其家庭和工作环境中暴露于BPA。 BPA暴露评估的常规方法依赖于笨重的实验室仪器，这些仪器具有较高的资本和运营支出，从而限制了可分析样品的数量。我们在这里报告了一种紧凑的便携式比色纸基生物传感设备的设计，该设备具有集成的采样/分析单元，用于基于现场测量室内粉尘中的BPA。该系统采用可互换的低成本纸质酶传感器作为BPA检测的测试区域，并与作为样品收集区域的空气采样盒相连接。传感器响应与浓度有关，检出限为0.28μg/ g。该传感器已通过常规气相色谱法验证，可用于检测57种家用粉尘样品中两种浓度下的BPA暴露，其家庭粉尘中的BPA浓度范围为0.05至3.87μg/ g。讨论了这种方法在粉尘样品现场测量中的潜力。

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  • 来源
    《Environmental Science & Technology》 |2015年第16期|9889-9897|共9页
  • 作者

    Ramiz S. J. Alkasir; Alan Rossner; Silvana Andreescu;

  • 作者单位

    Department of Chemistry and Bimolecular Science, Clarkson University, Potsdam, New York 13699-5810, United States;

    Institute for a Sustainable Environment, Clarkson University, Potsdam, New York 13699-5715, United States;

    Department of Chemistry and Bimolecular Science, Clarkson University, Potsdam, New York 13699-5810, United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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