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首页> 外文期刊>Environmental Science & Technology >Urinary Concentrations of Bisphenol A and Three Other Bisphenols in Convenience Samples of U.S. Adults during 2000-2014
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Urinary Concentrations of Bisphenol A and Three Other Bisphenols in Convenience Samples of U.S. Adults during 2000-2014

机译：2000-2014年美国成年人便捷性样本中双酚A和其他三种双酚的尿液浓度

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摘要

Because of regulatory actions and public concerns, the use of bisphenol A (BPA) may decrease, while the use of BPA alternatives may increase. Although BPA alternatives are considered safer than BPA, their effects on health are still largely unknown. For risk assessment, understanding exposure to these chemicals is necessary. We measured the urinary concentrations of BPA and three bisphenol analogs, bisphenol S (BPS), bisphenol F (BPF), and bisphenol AF (BPAF), in 616 archived samples collected from convenience samplings of U.S. adults at eight time points between 2000 and 2014. We detected BPA at the highest frequency and geometric mean (GM) concentrations (74-99%, 0.36-2.07 μg/L), followed by BPF (42-88%, 0.15-0.54 μg/L) and BPS (19-74%, ＜ 0.1-0.25 μg/L); BPAF was rarely detected (＜3% of all samples). Although concentrations of BPF were generally lower than for other bisphenols, the 95th percentile concentration of BPF was often comparable or higher than that of BPA. We did not observe obvious exposure trends for BPF. However, the significant changes in GM concentrations of BPA and BPS suggest that exposures may be declining (BPA) or on the rise (BPS). Nationally representative data will be useful to confirm these findings and to allow monitoring future exposure trends to BPA and some of its bisphenol alternatives.
机译：由于监管措施和公众关注，双酚A（BPA）的使用可能会减少，而BPA替代品的使用可能会增加。尽管双酚A替代品被认为比双酚A更安全，但它们对健康的影响仍然未知。为了进行风险评估，必须了解这些化学物质的暴露程度。我们在2000年至2014年之间的八个时间点，从美国成年人的便捷抽样中收集了616个归档样本，测量了BPA和三种双酚类似物，双酚S（BPS），双酚F（BPF）和双酚AF（BPAF）的尿中浓度。我们检测到最高频率和几何平均（GM）浓度（74-99％，0.36-2.07μg/ L）的BPA，其次是BPF（42-88％，0.15-0.54μg/ L）和BPS（19- 74％，＜0.1-0.25μg/ L）;很少检测到BPAF（占所有样本的<3％）。尽管BPF的浓度通常低于其他双酚，但BPF的95％浓度通常与BPA相当或更高。我们没有观察到BPF的明显暴露趋势。但是，BPA和BPS的GM浓度的显着变化表明，暴露量可能正在下降（BPA）或上升（BPS）。具有国家代表性的数据将有助于确认这些发现，并有助于监测BPA及其双酚替代品的未来暴露趋势。

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  • 来源
    《Environmental Science & Technology》 |2015年第19期|11834-11839|共6页
  • 作者

    Xiaoyun Ye; Lee-Yang Wong; Josh Kramer; Xiaoliu Zhou; Tao Jia; Antonia M. Calafat;

  • 作者单位

    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States;

    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States;

    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States;

    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States;

    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States;

    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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