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首页> 外文期刊>Environmental Science & Technology >Tissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid F-53B in Crucian Carp (Carassius carassius): Evidence for a Highly Bioaccumulative Contaminant of Emerging Concern
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Tissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid F-53B in Crucian Carp (Carassius carassius): Evidence for a Highly Bioaccumulative Contaminant of Emerging Concern

机译:Cru鱼(Carassius carassius)中氯化多氟烷基醚磺酸F-53B的组织分布和全身负担:新兴生物高度累积污染物的证据。

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摘要

Following the global actions to phase out perfluoroctanesulfonic acid (PFOS) a large number of alternative per- and polyfluoroalkyl substances, with poorly defined hazard properties, are being used in increasing quantities. Here, we report on the first detection of the chlorinated polyfluoroalkyl ether sulfonic acid F-S3B in biological samples and determine the tissue distribution and whole body bioaccumulation factors (BAF_(whole boby)) in crucian carp (Carassius carassius). Analysis of fish samples from Xiaoqing River (XR) and Tangxun Lake (TL) demonstrated a similar level of F-53B contamination with median concentrations in blood of 41.9 and 20.9 ng/g, respectively. Tissue/blood ratios showed that distribution of F-53B primarily occurs to the kidney (TL: 0.48, XR: 0.54), gonad (TL: 0.36, XR: 0.54), liver (TL: 0.38, XR: 0.53), and heart (TL: 0.47, XR 0.47). Median Log BAF_(whole boby) values for F-53B (XR: 4.124, TL: 4.322) exceeded regulatory bioaccumulation criterion and were significantly higher than those of PFOS in the same data sets (XR: 3.430, TL: 3.279). On the basis of its apparent omnipresence and strong bioaccumulation propensity, it is hypothesized that F-53B could explain a significant fraction of previously unidentified organofluorine in biological samples from China, and regulatory actions for this compound are encouraged.
机译:在采取逐步淘汰全氟辛烷磺酸(PFOS)的全球行动之后,越来越多的人使用了大量危害性不清的替代性全氟和多氟烷基物质。在这里,我们报道了在生物样品中首次检测到氯化多氟烷基醚磺酸F-S3B,并确定了carp鱼(Carassius carassius)的组织分布和全身生物累积因子(BAF_(whole boby))。对小清河(XR)和塘x湖(TL)的鱼样品进行的分析表明,F-53B污染水平相似,血液中位浓度分别为41.9 ng / g和20.9 ng / g。组织/血液比率显示F-53B的分布主要发生在肾脏(TL:0.48,XR:0.54),性腺(TL:0.36,XR:0.54),肝脏(TL:0.38,XR:0.53)和心脏中(TL:0.47,XR 0.47)。 F-53B(XR:4.124,TL:4.322)的Log Log BAF_(整个boby)值中位数超过了法规规定的生物蓄积标准,并且在相同数据集中(XR:3.430,TL:3.279)明显高于PFOS。根据其明显的无处不在和强大的生物蓄积倾向,据推测F-53B可以解释中国生物样品中以前未鉴定的有机氟的很大一部分,因此鼓励对该化合物进行管制。

著录项

  • 来源
    《Environmental Science & Technology》 |2015年第24期|14156-14165|共10页
  • 作者单位

    State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Science, Chinese Academy of Sciences, Beijing 100085, China;

    Department of Environmental Science and Analytical Chemistry (ACES), Stockholm University, Stockholm SE 106 91, Sweden;

    Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education, Jianghan University, Wuhan 430056, China;

    State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Science, Chinese Academy of Sciences, Beijing 100085, China;

    State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Science, Chinese Academy of Sciences, Beijing 100085, China;

    Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education, Jianghan University, Wuhan 430056, China,Institute of Environment and Health, Jianghan University, Wuhan 430056, China;

    State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Science, Chinese Academy of Sciences, Beijing 100085, China,Institute of Environment and Health, Jianghan University, Wuhan 430056, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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