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首页> 外文期刊>Environmental Science & Technology >Lethal and Sublethal Effects of Imidacloprid, After Chronic Exposure, On the Insect Model Drosophila melanogaster
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Lethal and Sublethal Effects of Imidacloprid, After Chronic Exposure, On the Insect Model Drosophila melanogaster

机译:慢性暴露后吡虫啉对昆虫模型果蝇的致死和亚致死作用

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摘要

Neonicotinoids are subjected to vigilance because of environmental contaminations and deleterious effects on bees. Imidacloprid (IMI) is one of the most representative insecticides of this family. At chronic exposure, concentration-effect relationships are non linear. An insect model should allow a better description of this toxicity. We compared the lethal concentration 50% (LC50) of IMI for a Drosophila-field strain, after acute and chronic exposure. Relative to the acute LC50, the chronic LC50 was lowered by a factor of 29 for males (1.3 mM/45 μM), 52 for larvae (157 μM/3 μM) and more than 172 for females (>3.1 mM/18 μM). Chronic exposure also revealed significant lethal and sublethal effects, at concentrations 3-5 orders of magnitude lower than the chronic LCSO. Mean mortalities reached 28% (at 3.91 nM) and 27% (at 39.1 nM) for females and males, respectively. Fecundity decreased of 16% at 1.96 nM. Mating increased of 30% at 0.391 nM. The LOEC (lowest observed effect concentration: 0.391 nM) was 46 000 times lower than the chronic LCSO for males; it was 115 000 times lower than the chronic LC50 for females. This study illuminates effects that neonicotinoids can induce at very low concentrations. This is of particular interest for nontarget insects and for insect dependent species.
机译:由于环境污染和对蜜蜂的有害影响,新烟碱类受到警惕。吡虫啉(IMI)是该家族中最具代表性的杀虫剂之一。在长期暴露下,浓度-效应关系是非线性的。昆虫模型应该可以更好地描述这种毒性。我们比较了果蝇田间菌株在急性和慢性暴露后的IMI致死浓度50%(LC50)。相对于急性LC50,男性的慢性LC50降低了29倍(1.3 mM / 45μM),幼虫降低了52倍(157μM/ 3μM),女性超过172倍(> 3.1 mM / 18μM) 。慢性暴露也显示出明显的致死和亚致死作用,其浓度比慢性LCSO低3-5个数量级。女性和男性的平均死亡率分别达到28%(3.91 nM)和27%(39.1 nM)。生殖力在1.96 nM时降低了16%。交配增加了30%,为0.391 nM。 LOEC(观察到的最低效应浓度:0.391 nM)比男性的慢性LCSO低46 000倍;它比女性慢性LC50低11.5万倍。这项研究阐明了新烟碱可以在非常低的浓度下诱导的作用。这对于非目标昆虫和昆虫依赖性物种特别重要。

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  • 来源
    《Environmental Science & Technology》 |2014年第7期|4096-4102|共7页
  • 作者单位

    Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique, 45071 Orleans, France;

    Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique, 45071 Orleans, France;

    Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique, 45071 Orleans, France;

    Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique, 45071 Orleans, France;

    Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique, 45071 Orleans, France;

    Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique, 45071 Orleans, France,Universite d'Orleans, 45100 Orleans, France;

    Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique, 45071 Orleans, France,Universite d'Orleans, 45100 Orleans, France;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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