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Multiresidue Analysis of Pesticides in Urine of Healthy Adult Companion Dogs

机译:健康成年伴侣狗尿液中农药的多残留分析

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摘要

The objective of this study was to determine the background exposures to pesticides as detected in urine from 21 healthy companion dogs in Northern Colorado. A panel of 301 pesticides was used to screen urine samples collected from dogs using an established ultraperformance liquid chromatography-mass spectrometry (UPLC-MS/MS) platform. Canine food intakes were controlled for one month on diets that were also screened for pesticide contents. Fifteen distinct pesticides were detected in urine. The most frequently detected compounds in canine urine samples collected over a 1 month period were atrazine, fuberidazole, imidacloprid, terbumeton, and clopyralid. Fuberidazole was the only pesticide detected in both the diets and urine. Companion dogs develop many similar chronic diseases as humans and represent a relevant model for biomonitoring combinations of environmental pesticide exposures, as well as for evaluating the potential relationships between environmental exposures and disease risk.
机译:这项研究的目的是确定在科罗拉多州北部的21只健康伴侣狗的尿液中检测到的农药暴露本底。使用建立的超高效液相色谱-质谱(UPLC-MS / MS)平台,使用一组301种农药筛选狗的尿液样品。饮食中的犬类食物摄入量控制了一个月,而且还要筛查农药含量。尿液中检测到15种不同的农药。在1个月内收集的犬尿液样品中最常检测到的化合物是阿特拉津,氟哌啶唑,吡虫啉,特布美顿和氯吡格雷。在饮食和尿液中均检出富贝唑。伴侣犬发展出与人类相似的许多慢性疾病,并代表了相关模型来对环境农药暴露进行生物监测,并评估环境暴露与疾病风险之间的潜在关系。

著录项

  • 来源
    《Environmental Science & Technology》 |2014年第24期|14677-14685|共9页
  • 作者单位

    Department of Clinical Sciences College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1680 Campus Delivery, Fort Collins, Colorado 80523-1680, United States;

    Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1680 Campus Delivery, Fort Collins, Colorado 80523-1680, United States;

    Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1680 Campus Delivery, Fort Collins, Colorado 80523-1680, United States;

    Department of Clinical Sciences College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1680 Campus Delivery, Fort Collins, Colorado 80523-1680, United States;

    Department of Clinical Sciences College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1680 Campus Delivery, Fort Collins, Colorado 80523-1680, United States,Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1680 Campus Delivery, Fort Collins, Colorado 80523-1680, United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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