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首页> 外文期刊>Environmental Science & Technology >Bioavailability, Toxicity and Biotransformation of Selenium in Midge (Chironomus dilutus) Larvae Exposed via Water or Diet to Elemental Selenium Particles, Selenite, or Selenized Algae
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Bioavailability, Toxicity and Biotransformation of Selenium in Midge (Chironomus dilutus) Larvae Exposed via Water or Diet to Elemental Selenium Particles, Selenite, or Selenized Algae

机译:通过水或饮食暴露于元素硒颗粒,亚硒酸盐或硒藻中的Mid(Chironomus dilutus)幼虫中硒的生物利用度,毒性和生物转化

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摘要

Elemental selenium (Se) is generally considered to be biologically inert due to its insolubility in water. It is a common form of Se in sediment near uranium mining and milling operations in northern Saskatchewan, Canada. Nanosized particles of many materials exhibit different properties compared with their bulk phases, in some cases posing health and ecological risks. Here we investigated the bioavailability and toxicity of Se nanoparticles (SeNPs) using 10-day waterborne and dietary exposures to larvae of Chironomus dilutus, a common benthic invertebrate. For comparison, larvae were also exposed to waterborne dissolved selenite and to dietary selenomethionine as selenized algae. Larval Se accumulation was evaluated using graphite furnace atomic absorption spectroscopy or inductively coupled plasma mass spectroscopy for total Se and X-ray absorption spectroscopy for Se chemical speciation. Exposure to nanoparticulate Se resulted in Se bioaccumulation, at high concentrations, inhibiting larval growth in both waterborne and dietary exposures; larvae predominantly accumulated selenomethionine-like species regardless of uptake route or form of Se tested. Despite the observed Se accumulation, our findings suggest there is little risk of direct SeNP toxicity to benthic invertebrates in Se-contaminated sediments in northern Saskatchewan. Nevertheless, elemental Se in sediments may be biologically available and may contribute directly or indirectly to the risk of Se toxicity to egg-laying vertebrates (fish and piscivorous birds) in Se-contaminated aquatic systems. It thus may be necessary to include elemental Se as a source of potential Se exposure in ecological risk assessments.
机译:由于硒元素在水中的不溶性,因此通常被认为具有生物惰性。它是加拿大萨斯喀彻温省北部铀矿开采和选矿附近沉积物中硒的一种常见形式。与本体相相比,许多材料的纳米颗粒表现出不同的特性,在某些情况下会带来健康和生态风险。在这里,我们使用10天的水基和饮食暴露于普通底栖无脊椎动物Chironomus dilutus的幼虫,研究了Se纳米颗粒(SeNPs)的生物利用度和毒性。为了进行比较,幼虫还暴露于水溶的亚硒酸盐和作为硒化藻类的饮食硒代蛋氨酸中。使用石墨炉原子吸收光谱法或感应耦合等离子体质谱法对总硒进行幼虫硒积累的评估,对于硒化学形态用X射线吸收光谱法进行评估。暴露于纳米颗粒的硒导致高浓度的硒生物积累,从而抑制了水和饮食中幼虫的生长;幼虫主要积累类似硒代蛋氨酸的物种,而与硒的摄取途径或硒形式无关。尽管观察到了硒的积累,但我们的研究结果表明,在萨斯喀彻温省北部被硒污染的沉积物中,对底栖无脊椎动物直接产生SeNP毒性的风险很小。然而,沉积物中的元素硒可能是生物学上可获得的,并且可能直接或间接地导致硒对受硒污染的水生系统中产卵脊椎动物(鱼类和食鱼鸟类)的毒性毒性风险。因此,可能有必要在生态风险评估中将元素硒作为潜在的硒暴露源。

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  • 来源
    《Environmental Science & Technology》 |2013年第1期|584-592|共9页
  • 作者单位

    Toxicology Centre, University of Saskatchewan, 44 Campus Drive, Saskatoon, Saskatchewan S7N 5B3, Canada,Department of Geological Sciences, University of Saskatchewan, 114 Science Place, Saskatoon, Saskatchewan S7N 5E2, Canada;

    Toxicology Centre, University of Saskatchewan, 44 Campus Drive, Saskatoon, Saskatchewan S7N 5B3, Canada;

    Department of Geological Sciences, University of Saskatchewan, 114 Science Place, Saskatoon, Saskatchewan S7N 5E2, Canada;

    Department of Geological Sciences, University of Saskatchewan, 114 Science Place, Saskatoon, Saskatchewan S7N 5E2, Canada;

    Toxicology Centre, University of Saskatchewan, 44 Campus Drive, Saskatoon, Saskatchewan S7N 5B3, Canada;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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