...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental Science & Technology >Determining the Relative Importance of Dietborne and Waterborne Toxicity of 4-tert-Butylphenol and 4-tert-Octylphenol to the Benthic Crustacean, Heterocypris incongruens
【24h】

Determining the Relative Importance of Dietborne and Waterborne Toxicity of 4-tert-Butylphenol and 4-tert-Octylphenol to the Benthic Crustacean, Heterocypris incongruens

机译：确定4-叔丁基苯酚的饮食和水性毒性的相对重要性和4-叔丁基苯酚和4-叔辛基苯酚对底皮甲壳类动物，杂交丙蛋白杂交

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Organic pollutants with high solid-water equilibrium partition coefficients are adsorbed into solid particles and are easily ingested by benthic organisms, potentially causing dietborne toxicity. Whether dietborne toxicity is more important than waterborne toxicity for such chemicals remains to be determined. In this study, we identify the most relevant uptake route for the toxicity of two alkylphenols, 4-tert-butylphenol (4tBP), and 4-tert-octylphenol (4tOP). To achieve this, 6-day toxicity tests under two exposure conditions, namely dietary exposure (clean water + contaminated food) and combined exposure (contaminated water + contaminated food) were conducted on a benthic ostracod, Heterocypris incongruens. The toxicologically important exposure routes were confirmed by the consistency of dietary and aqueous dose-response relationships under different exposure conditions. During the test, frequent renewal of water and food was performed to reduce variability in the exposure conditions. The results showed that, under the equilibrium condition, the dietary exposure route was toxicologically more important than the aqueous route for 4tBP, whereas the waterborne exposure route was more important than the dietary exposure route for 4tOP. This study provides a novel approach to identify the most relevant uptake pathways for chemical toxicity, which better explains the importance of exposure routes in toxicity effects.
机译：具有高固水平衡分配系数的有机污染物被吸附成固体颗粒，并且容易被底栖生物摄取，可能导致饮食毒性。饮食毒性比水性毒性更重要，这些化学品仍有待确定。在该研究中，我们鉴定了两种烷基酚，4-叔丁基苯酚（4TBP）和4-叔辛基苯酚（4TOP）的毒性最相关的摄取途径。为实现这一目标，在两个曝光条件下进行6天的毒性测试，即膳食暴露（清洁水+污染的食物）和组合暴露（受污染的水+污染的食物）在Benthic Ostracod，Heterocypris Incongruens上进行。在不同暴露条件下的膳食和水剂量反应关系的一致性证实了毒物学上重要的暴露途径。在测试期间，进行频繁更新水和食物以降低暴露条件的可变性。结果表明，在平衡条件下，膳食暴露途径比4TBP的含水途径更重要，而水性暴露途径比4TOP的膳食暴露途径更重要。本研究提供了一种新的方法来鉴定化学毒性最相关的摄取途径，这更好地解释了暴露途径在毒性效应中的重要性。

著录项

  • 来源
    《Environmental Science & Technology》 |2021年第12期|7939-7948|共10页
  • 作者

    Yilu Gu; Tomohiro Tobino; Fumiyuki Nakajima;

  • 作者单位

    Key Laboratory of the Three Gorges Reservoir Region's Eco-Environment Ministry of Education Chongqing University Chongqing 400045 China Department of Urban Engineering The University of Tokyo Tokyo 113-8656 Japan Fourth Institute of Oceanography Ministry of Natural Resources Beihai 536000 China;

    Department of Urban Engineering The University of Tokyo Tokyo 113-8656 Japan;

    Environmental Science Center The University of Tokyo Tokyo 113-0033 Japan;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    alkylphenol; toxicity test; dietborne toxicity; exposure route; Heterocypris incongruens; ISO 14371;

    机译：烷基酚;毒性测试;饮食毒性;曝光路线;handocypris Incongruens;ISO 14371.;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号