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首页> 外文期刊>Environmental Science & Technology >Engineered Nanoparticles May Induce Genotoxicity
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Engineered Nanoparticles May Induce Genotoxicity

机译：工程纳米颗粒可能会导致基因毒性

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摘要

Dramatically increased engineered nanoparticle (ENP) use has resulted in much greater potential for environmental and human exposures to these materials. Although receptor responses to ENP exposure can be low,most of the literature indicates toxicity by a wide range of measures. For plants,the most common toxic responses include reduced germination or growth,membrane damage,impaired photosynthesis,slowed or reduced reproductive development,and mortality. Commonly described toxic responses for animals exposed to ENPs include cytotoxicity by necrosis or apoptosis,tissue or organ-level damage,growth inhibition,impaired reproduction and/or development,and mortality. Although humans may not be exposed to high levels of ENPs occupationally,widespread low dose exposure can occur through a variety of ENP-containing consumer products,including textiles,cosmetics,and food packaging,for which the potential risks are poorly understood.
机译：大大增加了工程纳米颗粒（ENP）的使用，已为环境和人类暴露于这些材料带来了更大的潜力。尽管受体对ENP暴露的反应可能很低，但是大多数文献都通过多种措施表明了毒性。对于植物而言，最常见的毒性反应包括发芽或生长减少，膜损伤，光合作用受损，生殖发育减慢或减少以及死亡率。对暴露于ENP的动物的常见毒性反应包括坏死或凋亡引起的细胞毒性，组织或器官水平的损伤，生长抑制，繁殖和/或发育受损以及死亡率。尽管人类可能不会在职业上接触高水平的ENP，但通过各种含ENP的消费产品（包括纺织品，化妆品和食品包装）可能会发生广泛的低剂量接触，对此潜在的风险知之甚少。

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  • 来源
    《Environmental Science & Technology》 |2013年第23期|13212-13214|共3页
  • 作者

    Huanhua Wang; Fengchang Wu; Wei Meng; Jason C. White; Patricia A.Holden; Baoshan Xing;

  • 作者单位

    State Key Laboratory of Environmentai Criteria and Risk Assessment,Chinese Research Academy of Environmental Sciences,Beijing 100012 China;

    State Key Laboratory of Environmentai Criteria and Risk Assessment,Chinese Research Academy of Environmental Sciences,Beijing 100012 China;

    State Key Laboratory of Environmentai Criteria and Risk Assessment,Chinese Research Academy of Environmental Sciences,Beijing 100012 China;

    Department of Analytical Chemistry,Connecticut Agricultural Experiment Station,123 Huntington Street,New Haven,Connecticut 06504,United States;

    Bren School of Environmental Science & Management,and the University of California Center for Environmental Implications of Nanotechnology,Santa Barbara,California,93016,United States;

    Stockbridge School of Agriculture,University of Massachusetts,Amherst,Massachusetts 01003,United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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