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首页> 外文期刊>Environmental Science & Technology >A Survey of Phthalates and Parabens in Personal Care Products from the United States and Its Implications for Human Exposure
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A Survey of Phthalates and Parabens in Personal Care Products from the United States and Its Implications for Human Exposure

机译：美国个人护理产品中邻苯二甲酸酯和对羟基苯甲酸酯的调查及其对人体暴露的影响

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摘要

Despite the widespread usage of phthalates and parabens in personal care products (PCPs), little is known about concentrations and profiles as well as human exposure to these compounds through the use of PCPs. In this study, nine phthalates and six parabens were determined in 170 PCPs (41 rinse-off and 109 leave-on), including 20 baby care products collected from Albany, New York. Phthalates were less frequently found in rinse-off PCPs but were more frequently found in perfumes (detection frequency of 100% for diethyl phthalate [DEP], 67% for dibutyl phthalate [DBP]), skin toners (90% for DEP), and nail polishes (90% for DBP). Parabens were found in ～40% of rinse-off products and ～60% of leave-on products. The highest concentrations of DEP, DBP, methyl- (MeP), ethyl- (EtP), propyl- (PrP), and butyl parabens (BuP) were on the order of 1000 μg per gram of the product. On the basis of amount and frequency of use of PCPs and the measured median concentrations of target analytes, the total dermal intake doses (sum of all phthalates or parabens) were calculated to be 0.37 and 31.0 μg/kg-bw/day for phthalates and parabens, respectively, for adult females. The calculated dermal intake of phthalates from PCPs was lower for infants and toddlers than for adult females. In contrast, dermal intake of parabens from PCPs by infants and toddlers was higher than that for adult females. The calculated maximum daily exposure dose of MeP, EtP, and PrP from PCPs ranged between 58.6 and 766 μg/kg- bw/day for infants and toddlers, which was 3 times higher than that calculated for adult females. PCPs are an important source of human exposure to parabens; the contribution of PCPs to phthalate exposure is low, except for DEP.
机译：尽管在个人护理产品（PCP）中广泛使用邻苯二甲酸盐和对羟基苯甲酸酯，但对于浓度和分布以及通过使用PCP人体暴露于这些化合物的了解甚少。在这项研究中，测定了170种五氯苯酚中的9种邻苯二甲酸盐和6种对羟基苯甲酸酯（41种漂洗剂和109种免洗剂），其中包括从纽约奥尔巴尼收集的20种婴儿护理产品。邻苯二甲酸盐在冲洗型五氯苯酚中较少见，而在香水中更常见（邻苯二甲酸二乙酯[DEP]为100％，邻苯二甲酸二丁酯[DBP]为67％），皮肤调色剂（DEP为90％）和指甲油（DBP为90％）。在〜40％的漂洗产品和〜60％的免洗产品中发现对羟基苯甲酸酯。 DEP，DBP，甲基（MeP），乙基（EtP），丙基（PrP）和对羟基苯甲酸丁酯（BuP）的最高浓度约为每克产品1000μg。根据五氯苯酚的使用量和使用频率以及目标分析物的测量中值浓度，计算出的总皮肤摄入剂量（所有邻苯二甲酸酯或对羟基苯甲酸酯的总和）分别为0.37和31.0μg/ kg-bw /天。对羟基苯甲酸酯，分别用于成年女性。计算得出的婴幼儿从五氯苯酚中摄取邻苯二甲酸盐的真皮摄入量低于成年女性。相比之下，婴幼儿从五氯苯酚中摄取的对羟基苯甲酸酯的皮肤摄入量高于成年女性。据计算，婴幼儿从五氯苯酚中得到的MeP，EtP和PrP的最大每日暴露剂量在58.6至766μg/ kg-bw /天之间，是成年女性的3倍。五氯苯酚是人类接触对羟基苯甲酸酯的重要来源。除DEP以外，五氯苯酚对邻苯二甲酸盐暴露的贡献很小。

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  • 来源
    《Environmental Science & Technology》 |2013年第24期|14442-14449|共8页
  • 作者

    Ying Guo; Kurunthachalam Kannan;

  • 作者单位

    Wadsworth Center, New York State Department of Health and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, New York 12201-0509, United States;

    Wadsworth Center, New York State Department of Health and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, New York 12201-0509, United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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