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Response to Comment on 'Timing of Increased Autistic Disorder Cumulative Incidence'

机译:对“自闭症累积发病率增加的时间”评论的回应

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摘要

We used three administrative data sets and one worldwide composite data set for autistic disorder (AD) cumulative incidence taken from the open literature for analysis in our paper. We agree with Carey3 that analysis of long-term epidemiological studies would be desirable and that there are a number of potential confounding issues associated with analysis of administrative databases. However, these data sets are the only ones available in the literature that were of sufficient record length for changepoint analysis (cumulative incidence data for at least 10 cohorts); and met our other inclusion criteria of AD cases reported for a specific birth cohort until at least age 5 and collected data at least between the late 1980s and the mid-1990s, since previous estimates for the increases in autism were within this range.
机译:在本文中,我们使用了来自公开文献的三个行政数据集和一个针对自闭症(AD)累积发生率的全球综合数据集进行了分析。我们同意Carey3的观点,对长期流行病学研究进行分析将是可取的,并且与管理数据库的分析相关联的还有许多潜在的混淆问题。但是,这些数据集是文献中仅有的,具有足够记录长度用于变更点分析的数据集(至少10个队列的累积发生率数据);并且符合我们的其他入选标准,因为至少在5岁之前报道了特定出生队列的AD病例,并且至少在1980年代末至1990年代中期之间收集了数据,因为先前对自闭症增加的估计在此范围内。

著录项

  • 来源
    《Environmental Science & Technology》 |2012年第3期|p.1950-1951|共2页
  • 作者单位

    National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, MD-B343-06, Research Triangle Park, North Carolina 27711, United States;

    National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, MD-B343-06, Research Triangle Park, North Carolina 27711, United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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