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Occurrence of Pharmaceuticals and Personal Care Products in German Fish Tissue: A National Study

机译:一项国家研究表明,德国鱼类组织中药物和个人护理产品的出现

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摘要

German Environment Specimen Bank (GESB) fish tissue samples, collected from 14 different GESB locations, were analyzed for 15 pharmaceuticals, 2 pharmaceutical metabolites, and 12 personal care products. Only 2 pharmaceuticals, diphenhydramine and desmethylsertraline, were measured above MDL. Diphenhydramine (0.04-0.07 ng g~(-1) ww) and desmethylsertraline (1.65-3.28 ng g~(-1) ww) were measured at 4 and 2 locations, respectively. The maximum concentrations of galaxolide (HHCB) (447 ng g~(-1) ww) and tonalide (AHTN) (15 ng g~(-1) ww) were measured at the Rehlingen sampling site in the Saar River. A significant decrease in HHCB and AHTN fish tissue concentrations was observed from 1995 to 2008 at select GESB sampling sites (r~2 = 0.69-0.89 for galaxolide and 0.89- 0.97 for tonalide with p < 0.003). Galaxolide and tonalide fish tissue concentrations in Germany were ~19X and ~28X lower, respectively, as compared to fish tissue concentrations measured in a United States nationwide PPCP study conducted in 2006. Proximity of the sampling locations to the upstream wastewater treatment plant discharging point and mean annual flow at the sampling location were found to significantly predict galaxolide and tonalide fish tissue concentrations (HHCB: r = 0.79, p = 0.021 and AHTN: r~2 = 0.81, p = 0.037) in Germany.
机译:从14个不同的GESB地点收集的德国环境标本库(GESB)鱼组织样本进行了分析,分析了15种药物,2种药物代谢产物和12种个人护理产品。在MDL之上仅测定了2种药物苯海拉明和去甲基舍曲林。分别在4个和2个位置测量了苯海拉明(0.04-0.07 ng g〜(-1)ww)和去甲基舍曲林(1.65-3.28 ng g〜(-1)ww)。在萨尔河的Rehlingen采样点测量了galaxolide(HHCB)(447 ng g〜(-1)ww)和tonalide(AHTN)(15 ng g〜(-1)ww)的最大浓度。从1995年到2008年,在选定的GESB采样点观察到HHCB和AHTN鱼组织浓度显着下降(galaxolide r〜2 = 0.69-0.89,tonalide 0.89- 0.97,p <0.003)。与2006年美国全国PPCP研究中测得的鱼组织浓度相比,德国的Galaxolide和Tonalide鱼组织浓度分别降低了约19倍和约28倍。采样位置靠近上游废水处理厂的排放点和在德国,采样点的年平均流量被发现可以显着预测galaxolide和tonalide鱼的组织浓度(HHCB:r = 0.79,p = 0.021和AHTN:r〜2 = 0.81,p = 0.037)。

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  • 来源
    《Environmental Science & Technology》 |2012年第16期|p.9047-9054|共8页
  • 作者单位

    Department of Chemistry and Biochemistry, Baylor University, Waco, Texas 76798, United States,Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, Texas 76798, United States;

    Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, Texas 76798, United States,Department of Environmental Science, Baylor University, Waco, Texas 76798, United States,The Institute of Ecological, Earth and Environmental Sciences, Baylor University, Waco, Texas 76798, United States;

    Department of Chemistry and Biochemistry, Baylor University, Waco, Texas 76798, United States,Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, Texas 76798, United States,The Institute of Ecological, Earth and Environmental Sciences, Baylor University, Waco, Texas 76798, United States;

    Umweltbundesamt, P.O. Box 330022, Berlin 14191, Germany;

    Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), 57392 Schmallenberg, Germany;

    Department of Biogeography, Trier University, 54286 Trier, Germany;

    Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, Texas 76798, United States,Department of Environmental Science, Baylor University, Waco, Texas 76798, United States,The Institute of Ecological, Earth and Environmental Sciences, Baylor University, Waco, Texas 76798, United States;

    Department of Chemistry and Biochemistry, Baylor University, Waco, Texas 76798, United States,Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, Texas 76798, United States,Department of Environmental Science, Baylor University, Waco, Texas 76798, United States,The Institute of Ecological, Earth and Environmental Sciences, Baylor University, Waco, Texas 76798, United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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