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Moving beyond Mass: The Unmet Need to Consider Dose Metrics in Environmental Nanotoxicology Studies

机译:超越质量:在环境纳米毒理学研究中未考虑剂量指标的需求

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摘要

The field of nanotechnology has rapidly developed due to recognition that nanoscale particles often exhibit properties that differ substantially from comparable bulk phases. Given this fact it is unfortunate that the environmental nanotoxicology community continues to rely heavily upon mass-based dose-metrics. To truly evaluate if nanoscale particles elicit toxicological responses that differ from those of bulk phases then alternative dose-metrics must be simultaneously considered.
机译:由于认识到纳米级颗粒通常表现出与可比的本体相显着不同的性质,因此纳米技术领域已经迅速发展。鉴于这一事实,不幸的是,环境纳米毒理学界继续严重依赖基于质量的剂量度量。为了真正评估纳米级颗粒是否引起与本体相不同的毒理学响应,必须同时考虑其他剂量指标。

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  • 来源
    《Environmental Science & Technology》 |2012年第20期|p.10881-10882|共2页
  • 作者单位

    Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States,Institute for Critical Technology and Applied Science (ICTAS), Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States,Center for the Environmental Implications of Nanotechnology (iCENT), Duke University, Durham, North Carolina, United States,NanoSafe, Inc., Blacksburg, Virginia, United States;

    U.S. Army Engineer Research and Development Center (ERDC), Vicksburg, Mississippi, United States;

    NanoSafe, Inc., Blacksburg, Virginia, United States;

    Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States,Institute for Critical Technology and Applied Science (ICTAS), Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States,Center for the Environmental Implications of Nanotechnology (iCENT), Duke University, Durham, North Carolina, United States;

    U.S. Army Engineer Research and Development Center (ERDC), Vicksburg, Mississippi, United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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