...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental Science & Technology >In Vitro Evaluation of Ferrihydrite as an Enterosorbent for Arsenic from Contaminated Drinking Water
【24h】

In Vitro Evaluation of Ferrihydrite as an Enterosorbent for Arsenic from Contaminated Drinking Water

机译：水铁矿作为饮用水中砷的肠溶吸收剂的体外评估

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Arsenic (As) is a toxic trace element found in groundwater due to natural and industrial processes. Exposure has been linked to cancers of the bladder, lungs, skin, kidneys, nasal passages, liver, and the prostate. Arsenic in drinking water is a problem in many countries, notably Bangladesh and Taiwan. The purpose of this research was to utilize binding isotherms, a simulated gastrointestinal (Gl) model, and the adult Hydra bioassay to evaluate ferrihydrite's potential to bind As and serve as a potential enterosorbent for As found in drinking water. A variety of clay minerals and synthesized iron oxides including ferrihydrite were screened for their ability to bind As(III), as sodium arsenite, and As(V), as sodium arsenate. After ferrihydrite was demonstrated to be the most effective sorbent for both As species, adsorption isotherms were performed. All isotherm data were fit to the Langmuir equation to determine adsorption capacity (Q_(max)). Ferrihydrite bound 96% of As(III) and 97% of As(V) in the screening studies and had a Q_(max) of 1.288 mol/kg for As(III) and 0.744 mol/kg for As(V). Using a simulated Gl model, ferrihydrite was found to effectively adsorb As(V) and As(III) in the stomach and intestine. Ferrihydrite (0.25% w/w) protected adurt Hydra at levels up to 200 times the minimal effective concentration (MEC) for As(III) and up to 2.5 times the MEC for As(V). These experiments confirm that ferrihydrite is a high capacity sorbent of As and that it is effective at removing As in a simulated Gl model. These results suggest that ferrihydrite could be used as a potential enterosorbent for As found in drinking water. Future work will focus on verifying ferrihydrite's safety and efficacy in vivo.
机译：砷（As）是自然和工业过程中在地下水中发现的有毒微量元素。暴露与膀胱癌，肺癌，皮肤癌，肾脏癌，鼻腔癌，肝癌和前列腺癌有关。在许多国家，尤其是孟加拉国和台湾，饮用水中的砷是一个问题。这项研究的目的是利用结合等温线，模拟胃肠道（Gl）模型和成人Hydra生物测定法来评估水铁矿结合砷的潜力，并作为饮用水中发现的砷的潜在肠吸收剂。筛选了各种粘土矿物和合成的铁氧化物，包括三水铁矿，它们具有作为砷化钠结合As（III）和作为砷酸钠结合As（V）的能力。在证明水铁矿是两种砷物种最有效的吸附剂后，进行了吸附等温线。将所有等温线数据拟合到Langmuir方程，以确定吸附容量（Q_（max））。在筛选研究中，水铁矿结合了96％的As（III）和97％的As（V），对于As（III）的Q_（max）为1.288 mol / kg，对于As（V）的Q_（max）为0.744 mol / kg。使用模拟的Gl模型，发现水铁矿可有效吸附胃和肠中的As（V）和As（III）。水铁矿（0.25％w / w）保护的Hydra，对As（III）的最小有效浓度（MEC）高达200倍，对As（V）的MEC高达2.5倍。这些实验证实了水铁矿是As的高容量吸附剂，并且在模拟的Gl模型中可以有效地去除As。这些结果表明，水铁矿可以用作饮用水中砷的潜在肠吸收剂。未来的工作将集中于验证体内水铁矿的安全性和有效性。

著录项

  • 来源
    《Environmental Science & Technology》 |2009年第14期|5501-5506|共6页
  • 作者

    J. F. TAYLOR; A. ROBINSON; N. JOHNSON; A. MARROQUIN-CARDONA; B. BRATTIN; R. TAYLOR; T. D. PHILLIPS;

  • 作者单位

    Department of Veterinary Integrative Biosciences, Texas A&M University, 4458 TAMU, College Station, Texas 77843;

    Department of Veterinary Integrative Biosciences, Texas A&M University, 4458 TAMU, College Station, Texas 77843;

    Department of Veterinary Integrative Biosciences, Texas A&M University, 4458 TAMU, College Station, Texas 77843;

    Department of Veterinary Integrative Biosciences, Texas A&M University, 4458 TAMU, College Station, Texas 77843;

    Department of Veterinary Integrative Biosciences, Texas A&M University, 4458 TAMU, College Station, Texas 77843;

    Department of Veterinary Integrative Biosciences, Texas A&M University, 4458 TAMU, College Station, Texas 77843;

    Department of Veterinary Integrative Biosciences, Texas A&M University, 4458 TAMU, College Station, Texas 77843;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号