...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental Science & Technology >Identification of Ah Receptor Agonists in Soil of E-waste Recycling Sites from Taizhou Area in China
【24h】

Identification of Ah Receptor Agonists in Soil of E-waste Recycling Sites from Taizhou Area in China

机译：台州地区电子垃圾回收场土壤中Ah受体激动剂的鉴定

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In recent years, increasing concern has surrounded the consequences of improper electric and electronic waste (e-waste) disposal. In order to mitigate or remediate the potentially severe toxic effects of e-waste recycling on the environment organisms, and humans, many contaminated sites must first be well-characterized. In this study, soil samples were taken from Taizhou city, one of the largest e-waste disposal centers in China, which was involved in recycling for nearly 30 years. The extracts of the samples were assayed for aryl hydrocarbon receptor (AhR)-mediated ethoxyresorufin-O-deethylase (EROD) induction in the rat hepatoma cell line H4IIE. Some of the target AhR agonists, including polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs), were instrumentally analyzed as well. The cause-effect relationship and dose-response relationship between the chemical concentrations of AhR agonists and observed EROD activity were examined. The results showed that soil extracts could induce AhR activity significantly, and the chemically derived 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) equivalents (TEQ_(cal)) were perfectly correlated to bioassay-derived TCDD equivalents (TEQ_(bio); R = 0.96, P < 0.001), which indicated that the known AhR agonists could account for the observed responses. Among different contributors, PCBs accounted for 87.2-98.2% and PCDD/Fs contributed 1.7-11.6% of TEQ_(cal), while the contribution of PAHs could almost be neglected. Under these conditions, a quantitative dose-effect relationship between
机译：近年来，越来越多的关注围绕着不当处置电子电气废物（电子废物）的后果。为了减轻或补救电子废物回收对环境生物和人类的潜在严重毒害作用，必须首先充分表征许多受污染的场所。在这项研究中，土壤样本取自中国最大的电子废物处理中心之一的台州市，该市参与了近30年的回收利用。在大鼠肝癌细胞系H4IIE中分析了样品提取物的芳基烃受体（AhR）介导的乙氧基间苯二酚-O-脱乙基酶（EROD）诱导。还对一些目标AhR激动剂进行了分析，包括多氯二苯并对二恶英和二苯并呋喃（PCDD / Fs），多氯联苯（PCB）和多环芳烃（PAH）。检查了AhR激动剂的化学浓度与所观察到的EROD活性之间的因果关系和剂量反应关系。结果表明，土壤提取物可以显着诱导AhR活性，化学衍生的2,3,7,8-四氯二苯并-对-二恶英（TCDD）当量（TEQ_（cal））与生物测定衍生的TCDD当量（TEQ_ （生物）； R = 0.96，P <0.001），这表明已知的AhR激动剂可以解释观察到的反应。在不同的贡献者中，多氯联苯占TEQ_（cal）的87.2-98.2％，而PCDD / F贡献了TEQ_（cal）的1.7-11.6％，而PAHs的贡献几乎可以忽略。在这些条件下，之间的定量剂量效应关系

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号