...
首页> 外文期刊>Environmental toxicology and chemistry >The Role of Epigenomics in Aquatic Toxicology
【24h】

The Role of Epigenomics in Aquatic Toxicology

机译:表观基因组学在水生毒理学中的作用

获取原文
获取原文并翻译 | 示例
           

摘要

Over the past decade, the field of molecular biology has rapidly incorporated epigenetic studies to evaluate organism-environment interactions that can result in chronic effects. Such responses arise from early life stage stress, the utilization of genetic information over an individual's life time, and transgenerational inheritance. Knowledge of epigenetic mechanisms provides the potential for a comprehensive evaluation of multigenerational and heritable effects from environmental stressors, such as contaminants. Focused studies have provided a greater understanding of how many responses to environmental stressors are driven by epigenetic modifiers. We discuss the promise of epigenetics and suggest future research directions within the field of aquatic toxicology, with a particular focus on the potential for identifying key heritable marks with consequential impacts at the organism and population levels. (C) 2017 SETAC
机译:在过去的十年中,分子生物学领域迅速整合了表观遗传学研究,以评估可能导致慢性影响的生物与环境之间的相互作用。这种反应来自生活早期的压力,个体一生中遗传信息的利用以及跨代遗传。表观遗传机制的知识为全面评估环境压力源(例如污染物)的多代遗传效应提供了潜力。重点研究提供了对表观遗传修饰因子驱动环境应激源反应的更多理解。我们讨论了表观遗传学的前景,并提出了水生毒理学领域内的未来研究方向,特别着重于识别对生物和种群水平有相应影响的关键遗传标记的潜力。 (C)2017年SETAC

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号