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首页> 外文期刊>Environmental toxicology and chemistry >PHYTOESTROGENS IN THE ENVIRONMENT, Ⅱ: MICROBIOLOGICAL DEGRADATION OF PHYTOESTROGENS AND THE RESPONSE OF FATHEAD MINNOWS TO DEGRADATE EXPOSURE
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PHYTOESTROGENS IN THE ENVIRONMENT, Ⅱ: MICROBIOLOGICAL DEGRADATION OF PHYTOESTROGENS AND THE RESPONSE OF FATHEAD MINNOWS TO DEGRADATE EXPOSURE

机译:环境中的植物性雌激素,Ⅱ:植物性雌激素的微生物降解及肥头对降解暴露的响应

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摘要

Phytoestrogens are endocrine active compounds derived from plants, including the isoflavones genistein and daidzein, and their methylated derivatives biochanin A and formononetin. These compounds have been detected at the μg/L level in the effluents of plant processing industries and municipal treatment plants and at the ng/L level in surface waters worldwide. The present study assessed the persistence of genistein and daidzein in natural aquatic systems, specifically riverine samples. Initial concentration, temperature, sample location, and time of sample collection varied. Genistein and daidzein were found to be readily biodegradable at all tested concentrations, at both 10 ℃ and 20 ℃, in samples collected during different seasons, and in samples from 3 different rivers. In addition, organismal responses in larval and sexually mature fathead minnows (Pimephales promelas) were quantified following exposure to microbiologically degraded phytoestrogens (genistein, daidzein, and formononetin). Products of the microbiological degradation of parent phytoestrogens did not affect larval survival, growth, or predator avoidance. Female adult fathead minnows exposed to these degradation products produced significantly fewer eggs than those exposed to a control, but no other morphological, physiological, or behavioral changes were observed with male or female minnows. The present research suggests that although phytoestrogens are not likely to persist in aquatic systems, they may pseudo-persist if discharges are continuous; in addition, caution should be exercised with respect to high-concentration effluents because of the potentially antiestrogenic effects of phytoestrogen degradates.
机译:植物雌激素是来源于植物的内分泌活性化合物,包括异黄酮染料木黄酮和黄豆苷元,以及它们的甲基化衍生物biochanin A和formononetin。在植物加工业和市政污水处理厂的废水中,以μg/ L的水平检测到这些化合物,而在全世界的地表水中,以ng / L的水平检测到了这些化合物。本研究评估了染料木素和黄豆苷元在天然水生系统中的持久性,特别是在河流样品中。初始浓度,温度,样品位置和样品收集时间各不相同。发现金雀异黄素和黄豆苷元在10℃和20℃的所有测试浓度下,在不同季节采集的样品以及在3条不同河流中的样品均易于生物降解。此外,在暴露于微生物降解的植物雌激素(染料木黄酮,黄豆苷元和formononetin)后,对幼虫和性成熟的黑头min鱼(Pimephales promelas)中的生物反应进行了定量。亲本植物雌激素的微生物降解产物不会影响幼虫的存活,生长或避免捕食。暴露于这些降解产物的成年fat头小now生产的卵比暴露于对照的成年fat头显着少,但是在雌雄min鱼中未观察到其他形态,生理或行为变化。目前的研究表明,尽管植物雌激素不太可能在水生系统中持续存在,但如果连续排放,它们可能会伪持久。此外,由于植物雌激素降解物可能具有抗雌激素作用,因此应谨慎处理高浓度废水。

著录项

  • 来源
    《Environmental toxicology and chemistry》 |2014年第3期|560-566|共7页
  • 作者单位

    Water Resources Science Graduate Program, University of Minnesota, St. Paul, Minnesota, USA;

    Department of Civil Engineering, University of Minnesota, St. Paul, Minnesota, USA;

    Aquatic Toxicology Laboratory, St. Cloud State University, St. Cloud, Minnesota, USA;

    Water Resources Science Graduate Program, University of Minnesota, St. Paul, Minnesota, USA,Department of Civil Engineering, University of Minnesota, St. Paul, Minnesota, USA;

    Aquatic Toxicology Laboratory, St. Cloud State University, St. Cloud, Minnesota, USA;

    Water Resources Science Graduate Program, University of Minnesota, St. Paul, Minnesota, USA,Department of Civil Engineering, University of Minnesota, St. Paul, Minnesota, USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Environmental fate; Endocrine disrupting compounds; Emerging pollutants; Phytoestrogens; Biodegradation;

    机译:环境命运;内分泌干​​扰化合物;新兴污染物;植物雌激素;生物降解;

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