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首页> 外文期刊>Environmental toxicology and chemistry >TRANSPLACENTAL TRANSFER OF POLYCHLORINATED BIPHENYLS AND POLYBROMINATED DIPHENYL ETHERS IN ARCTIC BELUGA WHALES (DELPHINAPTERUS LEU CAS)
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TRANSPLACENTAL TRANSFER OF POLYCHLORINATED BIPHENYLS AND POLYBROMINATED DIPHENYL ETHERS IN ARCTIC BELUGA WHALES (DELPHINAPTERUS LEU CAS)

机译：北极白鲸中多氯联苯和多溴化二苯醚的跨膜转移

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摘要

This study found that arctic beluga whales (Delphinapterus leucas) transferred, on average, 11.4% (7.5 mg) and 11.1% (0.1 mg) of their polychlorinated biphenyl (PCB) and polybrominated diphenyl ether (PBDE) blubber burden to their near-term fetuses. A single physicochemical parameter, log K_(OW) largely explained this transplacental transfer for PCBs (r~2 = 0.79, p < 0.00001) and PBDEs (r~2 = 0.37, p = 0.007), with congeners having a log K_(OW) < 6.5 preferentially transferred to the fetus. Blubber concentrations of 257 ng/g lipid weight (lw) PCBs and 3.8 ng/g (lw) PBDEs in beluga fetuses highlights the exposure to endocrine-disrupting compounds during a critical developmental stage. The implications of detecting these levels of legacy PCBs and the flame retardant PBDEs in unborn arctic beluga are unclear.
机译：这项研究发现，北极白鲸（Delphinapterus leucas）平均将其多氯联苯（PCB）和多溴联苯醚（PBDE）的油脂负担平均转移至近期的11.4％（7.5 mg）和11.1％（0.1 mg）胎儿一个单一的理化参数log K_（OW）在很大程度上解释了PCB（r〜2 = 0.79，p <0.00001）和PBDEs（r〜2 = 0.37，p = 0.007）的胎盘转移，同系物的log K_（OW ）<6.5优先转移至胎儿。白鲸胎儿中257 ng / g脂质重量（lw）的多氯联苯和3.8 ng / g（lw）PBDEs的含铅量突出表明，在关键的发育阶段暴露于破坏内分泌的化合物。在未出生的北极白鲸中检测这些水平的传统PCB和阻燃性PBDE的含义尚不清楚。

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