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Epigenetics for Ecotoxicologists

机译:生态毒理学家的表观遗传学

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A New Slant on Old Ideas Do genes define your destiny? The field of epigenetics examines how genes and the environment interact to form the basis of heredity and comes up with some surprising findings. We often think of deoxyribonucleic acid (DNA) as the sole physical basis for heredity, the genetic code that determines everything from eye and hair color to specific personality traits. The growing field of epigenetics suggests that this traditional paradigm is an oversimplification. Epigenetics is the study of factors that are heritable, but which occur by mechanisms other than changes in the DNA code itself. C.H. Waddington first used the term epigenetics in the early 1940s to describe "the interactions of genes with their environment, which bring the phenotype into being." Epi-
机译:旧观念的新倾向基因是否定义了您的命运?表观遗传学领域研究了基因和环境如何相互作用以形成遗传基础,并提出了一些令人惊讶的发现。我们经常认为脱氧核糖核酸(DNA)是遗传的唯一物理基础,遗传密码决定了从眼睛和头发的颜色到特定个性特征的一切。表观遗传学的发展领域表明,这种传统范式过于简单化了。表观遗传学是对可遗传的因素的研究,但是这些因素是通过DNA编码本身变化以外的机制发生的。 C.H.沃丁顿在1940年代初首次使用表观遗传学一词来描述“基因与其周围环境的相互作用,从而使表型成为现实。” Epi-

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