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首页> 外文期刊>Environmental toxicology and chemistry >METABOLISM AND DISTRIBUTION OFp,p'-DDT DURING FLIGHT OF THE WHITE-CROWNED SPARROW, ZONOTRICHIA LEUCOPHRYS
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METABOLISM AND DISTRIBUTION OFp,p'-DDT DURING FLIGHT OF THE WHITE-CROWNED SPARROW, ZONOTRICHIA LEUCOPHRYS

机译：p，p'-DDT在白冠稀疏飞蝇（Zonotrichia leukophrys）飞行过程中的代谢和分布

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摘要

This study evaluated the interactions of flight, fasting, and 1,1,1-trichloro-bis(4-chlorophenyl)ethane (p,p'ADDT) loading on residue metabolism and distribution in recently exposed white-crowned sparrows (Zonotrichia leucophrys). Female sparrows were dosed with 5 mg p,p'-DDT per kg body weight over 3 d. Following 1 d of recovery, sparrows were flown in a wind tunnel for up to 140 min, in 15-min blocks. Food was withheld from the start of the flight period until birds were euthanized. DDT, l,l-dichloro-2,2-bis(4 chlorophenyl)ethane (DDD), and 1,l-dichloro-2,2-bis(4-chlorophenyl)ethylene (DDE) were present in all tissues examined. 1-Chloro-2,2-bis(4-chlorophenyl)ethene (DDjx), l,l-bis(4-chlorophenyl)ethane (p,p'-DDη), and 2,2-bis(4-chlorophenyl)ethanol (p,p'-DDOH) were not found. Fasting did not significantly affect the rate of residue increase over time in any of the tissues examined. When sparrows flew and fasted simultaneousiy, fasting seldom contributed to an increase in tissue residues. However, the length of time flown was significantly correlated with increasing toxicant concentrations in the brain, kidney, and liver, effectively demonstrating the potential for brief flights to enhance mobilization of DDT and its metabolites. Dose, flight, and fasting also increased residues in brain tissue. These contaminant redistributions may have important ramifications on the stresses experienced by migratory birds.
机译：这项研究评估了飞行，禁食和1,1,1-三氯双（4-氯苯基）乙烷（p，p'ADDT）负载对最近暴露的白冠麻雀（Zonotrichia leucophrys）残留代谢和分布的相互作用。 。雌麻雀在3 d内每公斤体重服用5 mg p，p'-DDT。恢复1天后，将麻雀在风洞中飞行15分钟，最多飞行140分钟。从飞行期开始就停止食物，直到对鸟类实施安乐死为止。在所有检查的组织中都存在DDT，1,1-二氯-2,2-双（4-氯苯基）乙烷（DDD）和1,1-二氯-2,2-双（4-氯苯基）乙烯（DDE）。 1-氯-2,2-双（4-氯苯基）乙烯（DDjx），1,1-双（4-氯苯基）乙烷（p，p'-DDη）和2,2-双（4-氯苯基）找不到乙醇（p，p'-DDOH）。空腹没有显着影响任何被检查的组织中残留物随时间增加的速率。当麻雀飞行并同时禁食时，禁食很少会导致组织残留增加。但是，飞行时间的长短与脑，肾和肝中毒物浓度的增加显着相关，有效地证明了短暂飞行以增强DDT及其代谢物的动员的潜力。剂量，飞行和禁食也会增加脑组织中的残留物。这些污染物的重新分布可能会对候鸟产生的压力产生重要影响。

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