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首页> 外文期刊>Environmental toxicology and chemistry >INTERACTIONS OF CADMIUM AND ZINC IMPACT THEIR TOXICITY TO THE EARTHWORM APORRECTODEA CALIGINOSA
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INTERACTIONS OF CADMIUM AND ZINC IMPACT THEIR TOXICITY TO THE EARTHWORM APORRECTODEA CALIGINOSA

机译：镉和锌的相互作用会影响其对加州产线AP藜的毒性

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摘要

Individual and binary mixture effects of Cd and Zn on mortality of the earthworm Aporrectodea caliginosa were investigated in one soil type. Mutual, systemic interactions of Cd and Zn were assessed over a broad range of concentration combinations. Exposures were expressed as measured total concentrations in soil, porewater concentrations, and CaCl2-extractable concentrations. The Cd-Zn and Zn-Cd interactions in soil were estimated by comparing partition coefficients (Kd) of one metal in the presence and absence of the second metal. Simple patterns of mixture toxicity (additive, antagonistic, or synergistic) were evaluated by the toxic unit approach. The more complex patterns (dose ratio dependent or dose level dependent) were quantified by the MIXTOX model. The partitioning of Cd and Zn between soil and pore water was affected neither by their concentration nor presence of the other metal, and metal partitioning remained linear at all exposure levels tested. The effect of the Cd and Zn mixtures on mortality of A. caliginosa was mainly antagonistic, and the magnitude of antagonism (1.1- 2.7 toxic units) was dependent upon both the relative concentrations of Cd and Zn and the concentration magnitudes. Interactions of both metals occurred at the organism level and were manifested in terms of effects (28-d median lethal concentrations). The present study highlights the importance of identifying the relative influence of various interactions from external exposure to internal assimilation in evaluating mixture toxicity. Environ. Toxicol. Chem.
机译：在一种土壤类型中，研究了镉和锌对and的致死性的单独和二元混合作用。在广泛的浓度组合范围内评估了Cd和Zn的相互系统相互作用。暴露量表示为土壤中测得的总浓度，孔隙水浓度和CaCl2可提取浓度。通过比较存在和不存在第二种金属时一种金属的分配系数（Kd）来估算土壤中Cd-Zn和Zn-Cd的相互作用。通过毒性单位方法评估了混合物毒性的简单模式（累加，拮抗或协同）。通过MIXTOX模型量化更复杂的模式（取决于剂量比或剂量水平）。 Cd和Zn在土壤和孔隙水之间的分配不受其浓度或其他金属的存在的影响，并且在所有测试暴露水平下，金属分配均保持线性。 Cd和Zn混合物对A. caliginosa死亡率的影响主要是拮抗的，拮抗作用的大小（1.1-2.7毒性单位）取决于Cd和Zn的相对浓度以及浓度大小。两种金属的相互作用均发生在生物体水平上，并以影响（中位数28天致死浓度）表示。本研究强调了在评估混合物毒性中，确定从外部暴露到内部同化的各种相互作用的相对影响的重要性。环境。毒药。化学

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  • 来源
    《Environmental toxicology and chemistry》 |2011年第9期|p.2084-2093|共10页
  • 作者

    Hao Qiu; Martina G. VuvER; Willie J.G. M. Peunenburg;

  • 作者单位

    Institute of Environmental Sciences, Leiden University, Leiden, The Netherlands;

    Institute of Environmental Sciences, Leiden University, Leiden, The Netherlands;

    Institute of Environmental Sciences, Leiden University, Leiden, The Netherlands,National Institute of Public Health and the Environment, Bilthoven, The Netherlands;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    cadmium; zinc; soil; mixture toxicity; earthworm;

    机译：镉;锌泥;混合物毒性;蚯蚓;

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