TOXICOKINETIC-TOXICODYNAMIC MODELING OF QUANTAL AND GRADED SUBLETHAL ENDPOINTS: A BRIEF DISCUSSION OF CONCEPTS

著录项

• 来源
  《Environmental toxicology and chemistry》 |2011年第11期|p.2519-2524|共6页
• 作者

  Roman Ashauer; Annika Agatz; Carlo Albert; Virginie Ducrot; Nika Galic; Jan Hendriks; Tjalling Jager; Andreas Kretschmann; Isabel Oconnor; Mascha Nadine Rubach; Anna-Maija Nyman; Walter Schmitt; Julita Stadnicka; Paul J. Van Den Brink; Thomas G. Preuss;

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• 作者单位

  Eawag, Swiss Federal Institute of Aquatic Science and Technology, Duebendorf, Switzerland;

  The University of York, Heslington, York, United Kingdom;

  Eawag, Swiss Federal Institute of Aquatic Science and Technology, Duebendorf, Switzerland;

  INRA, Equipe Ecotoxicologie et Qualite des Milieux Aquatiques, Rennes, France;

  Alterra and Wageningen University, Wageningen, The Netherlands;

  Radboud University, Nijmegen, The Netherlands;

  Vrije Universiteit, Amsterdam, The Netherlands;

  Eawag, Swiss Federal Institute of Aquatic Science and Technology, Duebendorf, Switzerland;

  Eawag, Swiss Federal Institute of Aquatic Science and Technology, Duebendorf, Switzerland,Radboud University, Nijmegen, The Netherlands;

  Alterra and Wageningen University, Wageningen, The Netherlands,Vrije Universiteit, Amsterdam, The Netherlands;

  Eawag, Swiss Federal Institute of Aquatic Science and Technology, Duebendorf, Switzerland,ETH Zuerich, Institute of Biogeochemistry and Pollutant Dynamics, Ziirich, Switzerland;

  RWTH Aachen University, Aachen, Germany;

  Eawag, Swiss Federal Institute of Aquatic Science and Technology, Duebendorf, Switzerland,ETH Zuerich, Institute of Biogeochemistry and Pollutant Dynamics, Ziirich, Switzerland;

  Alterra and Wageningen University, Wageningen, The Netherlands;

  RWTH Aachen University, Aachen, Germany;

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• 原文格式 PDF
• 正文语种 eng
• 中图分类
• 关键词

  toxicity; dynamic energy budget; dose-response; adverse outcome pathway; mechanistic effect model;

  机译：毒性;动态能源预算;剂量反应不良结果途径;机械效应模型;