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首页> 外文期刊>Environmental toxicology and chemistry >COMPARATIVE TOXICITY OF TWO GLYPHOSATE FORMULATIONS (ORIGINAL FORMULATION OF ROUNDUP® AND ROUNDUP WEATHERMAX~®) TO SIX NORTH AMERICAN LARVAL ANURANS
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COMPARATIVE TOXICITY OF TWO GLYPHOSATE FORMULATIONS (ORIGINAL FORMULATION OF ROUNDUP® AND ROUNDUP WEATHERMAX~®) TO SIX NORTH AMERICAN LARVAL ANURANS

机译：两种草甘膦制剂（ROUNDUP®和ROUNDUP WEATHERMAX〜®的原始制剂）对六种北美幼虫的比较毒性

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摘要

The toxicity of two glyphosate formulations (the original formulation of Roundup~® and Roundup WeatherMAX~®) to six species of North American larval anurans was evaluated by using 96-h static, nonrenewal aqueous exposures. The 96-h median lethal concentration values (LC50) ranged from 1.80 to 4.22 mg acid equivalent (ae)/L and 1.96 to 3.26 mg ae/L for the original formulation of Roundup and Roundup WeatherMAX, respectively. Judged by LC50 values, four species were more sensitive to Roundup WeatherMAX exposures, and two species were more sensitive to the original formulation. Two of six species, Bufo fowleri (p < 0.05, F= 14.89, degrees of freedom [df] = 1) and Rana clamitans (p < 0.05, F = 18.46, df= 1), had significantly different responses to the two formulations tested. Increased sensitivity to Roundup WeatherMAX likely was due to differences in the surfactants or relative amounts of the surfactants in the two formulations. Potency slopes for exposures of the original formulation ranged from 24.3 to 92.5% mortality/ mg ae/L. Thresholds ranged from 1.31 to 3.68 mg ae/L, showing an approximately three times difference in the initiation of response among species tested. For exposures of Roundup WeatherMAX, slopes ranged from 49.3 to 84.2% mortality/mg ae/L. Thresholds ranged from 0.83 to 2.68 mg ae/L. Margins of safety derived from a simulated direct overspray were above 1, except for one species in exposures of Roundup WeatherMAX. Laboratory data based on aqueous exposures are conservative because of the lack of environmental ligands; however, these tests provide information regarding the relative toxicity between these two Roundup formulations.
机译：通过使用96小时静态，不更新的含水暴露量，评估了两种草甘膦制剂（Roundup®和RoundupWeatherMAX®的原始制剂）对六种北美幼虫无氧动物的毒性。对于原始配方的Roundup和Roundup WeatherMAX，其96小时中位致死浓度值（LC50）分别为1.80至4.22 mg酸当量（ae）/ L和1.96至3.26 mg ae / L。根据LC50值判断，四种对Roundup WeatherMAX暴露更敏感，而两种对原始配方更敏感。六个物种中的两个（Bufo fowleri（p <0.05，F = 14.89，自由度[df] = 1）和Rana clamitans（p <0.05，F = 18.46，df = 1））对两种配方的响应差异显着经过测试。对Roundup WeatherMAX的敏感性增加可能是由于两种配方中表面活性剂的差异或表面活性剂的相对含量所致。原始制剂暴露的潜能斜率在24.3至92.5％死亡率/ mg ae / L之间。阈值范围为1.31至3.68 mg ae / L，显示了受测物种之间响应启动的差异大约三倍。对于Roundup WeatherMAX的暴露，死亡率/ mg ae / L的斜率范围为49.3％至84.2％。阈值范围为0.83至2.68 mg ae / L。模拟的直接过喷所产生的安全裕度高于1，但Roundup WeatherMAX的暴露除外。由于缺乏环境配体，基于水暴露的实验室数据是保守的。但是，这些测试提供了有关这两种农达制剂之间相对毒性的信息。

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  • 来源
    《Environmental toxicology and chemistry》 |2011年第12期|p.2756-2761|共6页
  • 作者

    LATICE FuENTES; LINDSAY J. MOORE; JOHN H. RODGERS; WlLLIAM W. BOWERMAN; Gregory K. Yarrow; Wayne Y. Chao;

  • 作者单位

    Department of Forestry and Natural Resources, Clemson University, Clemson, South Carolina, USA;

    Department of Forestry and Natural Resources, Clemson University, Clemson, South Carolina, USA;

    Department of Forestry and Natural Resources, Clemson University, Clemson, South Carolina, USA;

    Department of Environmental Science and Technology, University of Maryland, College Park, Maryland, USA;

    Department of Forestry and Natural Resources, Clemson University, Clemson, South Carolina, USA;

    Department of Forestry and Natural Resources, Clemson University, Clemson, South Carolina, USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    roundup~®; glyphosate; polyethoxylated tallow amine; amphibian; tadpole;

    机译：综述〜®;草甘膦聚乙氧基牛脂胺;两栖动物蝌蚪;

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