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首页> 外文期刊>Environmental toxicology and chemistry >ASSESSMENT OF CONTAMINATION OF THE SVITAVA AND SVRATKA RIVERS IN THE CZECH REPUBLIC USING SELECTED BIOCHEMICAL MARKERS
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ASSESSMENT OF CONTAMINATION OF THE SVITAVA AND SVRATKA RIVERS IN THE CZECH REPUBLIC USING SELECTED BIOCHEMICAL MARKERS

机译：使用选定的生物化学标记评估捷克共和国的SVITAVA和SVRATKA河流的污染

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摘要

The aim of the present study is to assess aquatic ecosystem contamination using selected biochemical markers: cytochrome P450, ethoxyresorufin-O-deethylase (EROD), glutathione S-transferase (GST), tripeptide glutathione, vitellogenin, and 11-ketotestos-terone in chub (Leuciscus cephalus L.). Seven locations on the Svitava and Svratka rivers (in the Brno conurbation, Czech Republic) were assessed. The results were compared with the levels of the most important inductors of these biomarkers: organic pollutants hexachlorocyclohexane (HCH), hexachlorobenzene (HCB), DDT and its metabolites, polychlorinated biphenyls, and polycyclic aromatic hydrocarbons in bottom sediment, fish muscle, and semipermeable membrane devices (SPMDs) and metals in sediment. The highest levels of pollutants were observed at sites situated downstream from Brno, especially at Modfice and Rajhradice. Significant positive correlations (p < 0.05) were found between EROD activity and HCH concentration in SPMDs, and also between GST and EROD activity with HCB concentration in muscle, after adjusting for age.
机译：本研究的目的是使用选定的生化标记物评估水生生态系统的污染：细胞色素P450，乙氧基试卤灵-O-脱乙基酶（EROD），谷胱甘肽S-转移酶（GST），三肽谷胱甘肽，卵黄蛋白原和11-酮睾酮-萜烯（头状叶猴）。评估了Svitava和Svratka河上的七个位置（在捷克共和国布尔诺市）。将结果与这些生物标志物中最重要的诱导剂水平进行了比较：有机污染物六氯环己烷（HCH），六氯苯（HCB），滴滴涕及其代谢产物，多氯联苯和底部沉积物，鱼肉和半透膜中的多环芳烃装置（SPMD）和沉积物中的金属。在布尔诺下游的地点，尤其是在Modfice和Rajhradice，观察到最高的污染物水平。在调整年龄后，发现SPMD中EROD活性与HCH浓度之间以及肌肉中HCB浓度与GST和EROD活性之间呈显着正相关（p <0.05）。

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  • 来源
    《Environmental toxicology and chemistry》 |2010年第3期|p.541-549|共9页
  • 作者

    Jana Blahova; Marcela Havelkova; Kamila Kruzikova; Klara Hilscherova; Roman Halouzkal; Helena Modra; Roman Grabic; Jarmila Halirova; Jana Jurcikova; Tomas Ocelka; Danka Harustiakova; Zdenka Svobodova;

  • 作者单位

    Department of Veterinary Public Health and Toxicology, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1-3, Brno, 612 42, Czech Republic;

    Department of Veterinary Public Health and Toxicology, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1-3, Brno, 612 42, Czech Republic;

    Department of Veterinary Public Health and Toxicology, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1-3, Brno, 612 42, Czech Republic;

    Research Centre for Environmental Chemistry and Ecotoxicology, Masaryk University, Kamenice 126/3, Brno, 625 00, Czech Republic;

    Department of Pathological Morphology, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1-3, Brno, 612 42, Czech Republic;

    Department of Veterinary Public Health and Toxicology, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1-3, Brno, 612 42, Czech Republic;

    Institute of Public Health Ostrava, Partyzanske nam. 7, Ostrava, 702 00, Czech Republic;

    Czech Hydrometeorological Institute, Kroftova 43, Brno, 616 67, Czech Republic;

    Institute of Public Health Ostrava, Partyzanske nam. 7, Ostrava, 702 00, Czech Republic;

    Institute of Public Health Ostrava, Partyzanske nam. 7, Ostrava, 702 00, Czech Republic;

    Institute of Biostatistics and Analyses, Masaryk University, Kamenice 126/3, Brno, 625 00, Czech Republic;

    Department of Veterinary Public Health and Toxicology, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1-3, Brno, 612 42, Czech Republic;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    vitellogenin; 11-ketotestosterone; detoxifying enzymes; persistent organic pollutants; metals;

    机译：卵黄蛋白原11-酮睾酮;排毒酶;持久性有机污染物;金属;

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