• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental toxicology and chemistry >UPTAKE, ELIMINATION, AND BIOTRANSFORMATION OF AQUEOUS AND DIETARY DDT IN MARINE FISH
【24h】

UPTAKE, ELIMINATION, AND BIOTRANSFORMATION OF AQUEOUS AND DIETARY DDT IN MARINE FISH

机译：海洋鱼类中饮食DDT的摄取，消除和生物转化

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

To understand the biokinetics and potential risks of p,p'-dichlorodiphenyltrichloroethane (DDT) and its metabolites, p,p'-dichlorodiphenyldichloroethylene (DDE) and p,p'-dichlorodiphenyldichloroethane (DDD), in fish, we exposed the black sea breams (Acanthopagrus schlegeli) to aqueous and dietary DDTs and then evaluated the bioaccumulation, distribution, biotrans-formation, and elimination of DDTs under controlled laboratory conditions. The fish rapidly accumulated DDTs from both routes of exposure, particularly the gills and viscera. Elimination of DDTs following aqueous or dietary uptake was slow, and biotran-slocation of DDTs was significant during the exposure period but negligible during the depuration period. The biotransformation process was more significant following dietary exposure. During depuration, DDE was the major biotransformed product in the sea breams' carcasses while DDD was the major product in the gills and viscera. However, DDD had a significantly higher elimination rate than DDE and, subsequently, the fish retained more DDE in the body. Intraspecies variability in the elimination and biotransformation processes in fish was observed. We demonstrated that the route of exposure significantly affected the fate and biokinetics of DDTs in fish. The application of a dynamic model provided a tool for quantifying the elimination and biotransformation of DDT in fish. The present study provided insights into the bioaccumulation and biotransformation pathways of DDT in fish that could have important ecotoxicological implications.
机译：为了了解对鱼中p，p'-二氯二苯基三氯乙烷（DDT）及其代谢产物p，p'-二氯二苯基二氯乙烯（DDE）和p，p'-二氯二苯基二氯乙烷（DDD）的生物动力学和潜在风险，我们暴露了黑鲷（Acanthopagrus schlegeli）加入水和饮食中的滴滴涕，然后在受控的实验室条件下评估了滴滴涕的生物积累，分布，生物转化和消除。鱼从两种接触途径中迅速积累了滴滴涕，尤其是the和内脏。摄入水或饮食后消除DDT的速度很慢，并且DDT的生物转位在接触期间很明显，而在净化期间则可以忽略不计。饮食接触后，生物转化过程更为显着。在净化过程中，DDE是鲷鱼car体中主要的生物转化产物，而DDD是g和内脏中的主要产物。但是，DDD的清除率明显高于DDE，因此，鱼在体内保留了更多的DDE。观察到鱼类消除和生物转化过程中的种内变异性。我们证明了接触途径显着影响鱼中滴滴涕的命运和生物动力学。动态模型的应用为量化鱼类中滴滴涕的消除和生物转化提供了一种工具。本研究提供了对鱼类中滴滴涕的生物积累和生物转化途径的见解，这些途径可能具有重要的生态毒理学意义。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号