...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental toxicology and chemistry >EARLY-LIFE-STAGE TOXICITY IN OFFSPRING FROM EXPOSED PARENT MEDAKA, ORYZIAS LATIPES, TO MIXTURES OF TRIBUTYLTIN AND POLYCHLORINATED BIPHENYLS
【24h】

EARLY-LIFE-STAGE TOXICITY IN OFFSPRING FROM EXPOSED PARENT MEDAKA, ORYZIAS LATIPES, TO MIXTURES OF TRIBUTYLTIN AND POLYCHLORINATED BIPHENYLS

机译：从暴露的亲本中成虫，Oryzias脂菜到三叶草苷和多氯联苯混合物的早期生命毒性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The present study examined the effects of tributyltin (TBT), polychlorinated biphenyls (PCBs), and mixtures of both chemicals on reproduction in Japanese medaka, Oryzias latipes. For 21 d we gave groups of medaka freeze-dried brine shrimp flakes contaminated with a mixture of either 0, 1, 5, or 25 μg TBT g~(-1) plus 0 or 25 μg PCBs g~(-1). We measured the fecundity and fertility of the parent fish and assessed the deformity, hatchability, time-to-hatching, and swim-up failure rate of the next generation. Fertilization success in the third week of the administration period was significantly decreased by administration of 25 μg TBT g~(-1) (77%) compared with the control group (87%). Both TBT and PCBs were transferred maternally into the eggs of the next generation, causing early life-stage toxicity. Administration of 1 μg TBT g~(-1) was not toxic to embryological development, but abnormal eye development (i.e., small eyes or no eyes) occurred when TBT at the same concentration was mixed with PCBs (6.4%). Administration of TBT alone significantly decreased hatchability and increased swim-up failure, and administration of PCBs alone significantly increased time-to-hatching. Statistical analysis by two-way analysis of variance detected an interaction between TBT and PCBs in these three parameters. TBT induces abnormal development of the eyes, reduced hatchability, and increased swim-up failure, whereas PCBs delay time-to-hatching. Administration of mixtures of TBT and PCBs has more adverse effects on the developmental stage of medaka than does that of each chemical alone.
机译：本研究研究了三丁基锡（TBT），多氯联苯（PCBs）以及两种化学物质的混合物对日本三叶草（Oryzias latipes）繁殖的影响。在21天之内，我们给出了被0、1、5或25μgTBT g〜（-1）加0或25μgPCBs g〜（-1）的混合物污染的medaka冻干盐水虾片。我们测量了亲鱼的繁殖力和繁殖力，并评估了下一代鱼的畸形，孵化率，孵化时间和游泳失败率。与对照组（87％）相比，施用25μgTBT g〜（-1）（77％）可以显着降低施用期第三周的施肥成功率。 TBT和PCBs都通过母体转移到下一代卵中，从而导致生命早期阶段的毒性。施用1μgTBT g〜（-1）对胚胎发育无毒，但是当将相同浓度的TBT与PCBs（6.4％）混合时，会出现异常的眼睛发育（即小眼睛或没有眼睛）。单独施用TBT会大大降低孵化率并增加游泳失败率，而单独施用PCB会大大增加孵化时间。通过方差的双向分析进行的统计分析检测到这三个参数中TBT和PCB之间的相互作用。 TBT会导致眼睛异常发育，降低孵化率并增加游泳失败，而PCB会延迟孵化时间。与仅单独使用每种化学物质相比，施用三丁基锡和多氯联苯的混合物对青aka的发育阶段具有更大的不利影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号