...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental toxicology and chemistry >Effects of sulfachlorpyridazine in MS.3-arable land: a multispecies soil system for assessing the environmental fate and effects of veterinary medicines.
【24h】

Effects of sulfachlorpyridazine in MS.3-arable land: a multispecies soil system for assessing the environmental fate and effects of veterinary medicines.

机译：磺胺氯哒嗪在MS.3耕地中的影响：用于评估环境命运和兽药影响的多物种土壤系统。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A multispecies soil system (MS.3) has been used to evaluate the ecological effects of veterinary pharmaceuticals in soil as a result of routine agricultural practices. Different experimental conditions were tested and the variation of the different parameters was evaluated for a final design. A protocol for the MS.3-arable land is presented here. Emergence of seedlings, plant elongation and biomass, earthworm mortality, and soil microbial enzymatic activities have been selected as toxicological endpoints for soil organisms. Toxicity tests were conducted with the leachate on aquatic organisms (in vitro fish cell lines, daphnids, and algae). The system was used for assessing the effects of the antimicrobial sulfachlorpyridazine that was tested in triplicate at concentrations of 0.01, 1, and 100 mg/kg. The chemical was mixed uniformly with a 20-cm depth soil column to resemble the distribution of manure within arable soil. Reversible and nonreversible effects on soil enzymatic activities were observed at 1 and 100 mg/kg, respectively. Earthworms were not affected. Significant reduction of plant elongation and biomass was observed at the highest concentration. Degradation and leaching contributed to the dissipation of sulfachlorpyridazine from the soil column. The undiluted leachate was highly toxic to Daphnia magna. The parent chemical was assumed responsible for the leachate toxicity although the role of mobile metabolites could not be excluded fully. No significant effects were observed for green algae Chlorella vulgaris and for the rainbow trout established cell lines RTG-2 (rainbow trout gonads) and RTL-WI (rainbow trout liver). The MS.3 system offers a cost-effective experimental approach to measure simultaneously fate and effects of chemicals on a realistic soil system under controlled laboratory conditions. The advantages of using MS.3-effect endpoints are discussed.
机译：由于常规的农业实践，已使用多物种土壤系统（MS.3）评估了土壤中兽药的生态效应。测试了不同的实验条件，并评估了不同参数的变化以进行最终设计。这里介绍了MS.3耕地的协议。幼苗的出现，植物的伸长和生物量，earth的死亡率以及土壤微生物的酶活性已被选作土壤生物的毒理学终点。用渗滤液对水生生物（体外鱼类细胞系，水蚤和藻类）进行了毒性测试。该系统用于评估以0.01、1和100 mg / kg的浓度一式三份测试的抗菌药物磺胺氯哒嗪的作用。将化学品与20厘米深的土壤柱均匀混合，以类似于肥料在可耕土壤中的分布。分别以1和100 mg / kg观察到对土壤酶活性的可逆和不可逆作用。 were未受影响。在最高浓度下观察到植物伸长率和生物量显着降低。降解和浸出促使磺胺氯哒嗪从土壤柱中消散。未稀释的渗滤液对大型蚤（Daphnia magna）具有剧毒。尽管不能完全排除流动代谢物的作用，但假定母体化学品对渗滤液毒性负责。对于绿藻小球藻和虹鳟建立的细胞系RTG-2（虹鳟性腺）和RTL-WI（虹鳟肝），未观察到显着影响。 MS.3系统提供了一种经济高效的实验方法，可以在受控的实验室条件下同时测量化学品在现实土壤系统上的命运和影响。讨论了使用MS.3-effect端点的优点。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号