AN IN VITRO STUDY OF THE INTERACTION OF SEA-NINE~(~R) WITH RAT LIVER MITOCHONDRIA

MARCANTONIO BRAGADIN; BRUNO PAVONI; GUIDO SCUTARI; SABRINA MANHNTE

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AN IN VITRO STUDY OF THE INTERACTION OF SEA-NINE~(~R) WITH RAT LIVER MITOCHONDRIA

机译：SEA-NINE〜（〜R）与大鼠肝线粒体相互作用的体外研究

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摘要

The interactions of the antifouling compound Sea-Nine~(~R) with rat liver mitochondria have been studied. The results indicate that low doses of this compound inhibit adenosine 5′-triphosphate (ATP) synthesis. Further investigations indicate that ATP synthesis inhibition should be due to an interaction of Sea-Nine with the succinic dehydrogenase in the mitochondrial respiratory chain.

机译：研究了防污化合物Sea-Nine〜（〜R）与大鼠肝线粒体的相互作用。结果表明，低剂量的该化合物抑制5'-三磷酸腺苷（ATP）的合成。进一步的研究表明，ATP合成的抑制应归因于Sea-Nine与线粒体呼吸链中的琥珀酸脱氢酶的相互作用。

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来源
《Environmental toxicology and chemistry》 |2005年第5期|p.1074-1078|共5页
作者
MARCANTONIO BRAGADIN; BRUNO PAVONI; GUIDO SCUTARI; SABRINA MANHNTE;
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作者单位

Dipartimento di Scienze Ambientali, Universita di Venezia, DD 2137, 30123 Venezia, Italy;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类环境卫生、环境医学;毒物学（毒理学）;化学工业废物处理与综合利用;
关键词
mitochondria; sea-nine~(~R); 5′-triphosphate synthesis;

机译：线粒体;海九〜（〜R）;5′-三磷酸酯的合成;

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1. Studies on the activation in vitro of carnitine palmitoyltransferase I in liver mitochondria from normal, diabetic and glucagon-treated rats [J] . B D Grantham, V A Zammit The biochemical journal . 1987,第1期

机译：正常，糖尿病和胰高血糖素处理的大鼠肝线粒体中肉碱棕榈酰转移酶I的体外活化研究
2. Interactions between neuroleptics and CYP2C6 in rat liver - in vitro and ex vivo study. [J] . Haduch A, Ogorka T, Boksa J, Pharmacological reports: PR . 2005,第6期

机译：在大鼠肝脏和体外研究中，抗精神病药与CYP2C6之间的相互作用。
3. Interactions between neuroleptics and CYP2C6 in rat liver - in vitro and ex vivo study. [J] . Anna Haduch, Tomasz Ogórka, Jan Boksa, Pharmacological reports: PR . 2005,第6期

机译：在大鼠肝脏和体外研究中，抗精神病药与CYP2C6之间的相互作用。
4. In Vitro Metabolism Studies of the GABA_(A) Receptor Partial Agonist ~(14)C CP-409,092 and Sumatriptan in Human Liver Mitochondria Using HPLC/RAM/ESI/MS/MS [C] . Amin Kamel, Scott Obach, Kevin Colizza, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：使用HPLC / RAM / ESI / MS / MS / MS / MS / MS / MS / MS的GABA_（A）受体部分激动剂〜（14）C CP-409,092和Sumatriptan的体外代谢研究
5. CREATINE KINASE ISOENZYMES IN SERUM. A. IN VITRO STUDIES WITH RAT CK-1 AND HUMAN SERUM. B. APPARENT MITOCHONDRIAL CREATINE KINASE IN THE SERUM OF A PATIENT WITH METASTATIC CANCER TO THE LIVER [D] . HEINZ, JOHN WALTER. 1981

机译：血清中的肌酐激酶同工酶。 A.大鼠CK-1和人血清的体外研究。 B.肝转移癌患者血清中的线粒体肌氨酸激酶
6. Studies on the activation in vitro of carnitine palmitoyltransferase I in liver mitochondria from normal diabetic and glucagon-treated rats. [O] . B D Grantham, V A Zammit 1987

机译：正常糖尿病和胰高血糖素处理的大鼠肝线粒体中肉碱棕榈酰转移酶I的体外活化研究。
7. An in vitro study of the interaction of Sea-Nine with rat lever mitochondria [O] . M Bragadin, B. Pavoni, G. Scutari, 2005

机译：海九与大鼠杠杆线粒体相互作用的体外研究
8. Studies on the Mechanism of Action of the in vitro PGB(x) Effect. III. The Interaction between PGB(x) and Rat Liver Mitochondria [R] . Shmukler, H. W., Kwong, S. F., Zawryt, M. G., 1981

机译：体外pGB（x）作用机制的研究。 III。 pGB（x）与大鼠肝线粒体的相互作用

AN IN VITRO STUDY OF THE INTERACTION OF SEA-NINE~(~R) WITH RAT LIVER MITOCHONDRIA

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