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首页> 外文期刊>Environmental toxicology and chemistry >EFFECTS OF METAL AND ORGANOPHOSPHATE MIXTURES ON CERIODAPHNIA DUBIA SURVIVAL AND REPRODUCTION
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EFFECTS OF METAL AND ORGANOPHOSPHATE MIXTURES ON CERIODAPHNIA DUBIA SURVIVAL AND REPRODUCTION

机译：金属和有机磷混合物对杜鹃花生存和繁殖的影响

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The toxicity of mixtures of copper, zinc, and diazinon were determined for Ceriodaphnia dubia using 7-d survival and reproduction tests. Fifteen treatments, including combinations of the chemicals at 0, 25, 50, 75, and 100% of their individual median lethal concentrations, adding up to one toxic unit (TU) were tested. The TU was then used to classify each mixture response as additive, greater than additive, or less than additive. For survival, additive responses occurred in the 75% zinc plus 25% diazinon and the 50% copper plus 25% zinc plus 25% diazinon treatments. For reproduction, additive responses occurred in the 75% copper plus 25% zinc, 75% copper plus 25% diazinon, and 75% zinc plus 25% diazinon treatments. Copper and zinc played a greater role in toxicity than diazinon did. Less-than-additive interactions were found in all remaining mixtures, perhaps because of differences in mode of action between diazinon and metals. Consideration of dose-response curves can help to explain inconsistencies regarding toxic response in treatments with different ratios of the same chemicals. As TU percentages changed, mixture components were taken from different locations on differently shaped dose-response curves. Because most responses were less than additive, however, water-quality criteria based on individual concentrations probably are protective for most metal-organophosphate mixtures.
机译：使用7天存活和繁殖测试确定了铜，锌和二嗪农的混合物的毒性，从而对杜氏蜡毛藻进行了测定。测试了15种处理方法，包括以各自的中位数致死浓度的0％，25％，50％，75％和100％组合使用的化学药品，总共增加了一个毒性单位（TU）。然后，将TU用于将每种混合物响应分类为添加剂，大于添加剂或小于添加剂。为了生存，在75％的锌加25％的二嗪农和50％的铜加25％的锌加25％的二嗪农治疗中产生加性反应。为了繁殖，在75％的铜加25％的锌，75％的铜加25％的二嗪农和75％锌加25％的二嗪农处理中产生加性响应。铜和锌在毒性方面的作用比二嗪农更大。在所有剩余的混合物中发现了小于加性的相互作用，这可能是由于二嗪农和金属之间的作用方式不同。考虑剂量反应曲线可以帮助解释在使用相同化学物质的不同比例的治疗中有关毒性反应的不一致之处。随着TU百分比的变化，混合物成分从形状不同的剂量反应曲线的不同位置获取。但是，由于大多数响应都小于加性响应，因此基于单独浓度的水质标准可能对大多数金属-有机磷酸盐混合物具有保护作用。

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