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首页> 外文期刊>Environmental toxicology and chemistry >Microcosm tributyltin bioaccumulation and multibiomarker assessment in the blue mussel Mytilus edulis.
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Microcosm tributyltin bioaccumulation and multibiomarker assessment in the blue mussel Mytilus edulis.

机译：缩蓝贻贝Mytilus edulis中的缩微三丁基锡生物积累和多生物标志物评估。

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摘要

Blue mussels, Mytilus edulis, were exposed to two different concentrations of tributyltin (TBT) in seawater, 1,000 ng Sn/L (C1 experiment) and 10 ng Sn/L (C2 experiment), for 4 d, in order to evaluate the bioaccumulation of TBT by mussels Mytilus edulis in microcosms and to test the ability of a multimarkers analysis to determine the effects of TBT on the biochemical parameters in mussels. Tissue burdens of Mytilus edulis were 204 +/- 7 and 2,120 +/- 4 ng Sn/g TBT after the 4-d tests for the C2 and C1 experiments, respectively. Analyses of dissected organs and/or tissues demonstrated that TBT accumulated to the greatest extent in gills in the C1 experiment and in the digestive gland in the C2 experiment. Bioconcentration factors (BCFs) were 12,100 +/- 300 and 2,000 +/- 10 for mussels exposed in the C2 and C1 experiments, respectively. The four biomarkers used in this work were acetylcholinesterase (AChE), glutathione S-transferase (GST), catalase (CAT) activities, and thiobarbituric acid-reactive substances (TBARS) contents. No significant changes were observed in the measured enzyme activities or in TBARS concentration after the 4-d TBT exposure.
机译：将蓝贻贝（Mytilus edulis）暴露于海水中两种不同浓度的三丁基锡（TBT），1,000 ng Sn / L（C1实验）和10 ng Sn / L（C2实验）持续4 d，以评估生物积累贻贝贻贝在微观世界中的TBT的检测，并测试多标记分析以确定TBT对贻贝生化参数的影响的能力。在进行C2和C1实验的4-d试验后，紫草的组织负担为204 +/- 7和2120 +/- 4 ng Sn / g TBT。对解剖的器官和/或组织的分析表明，在C1实验中experiment和消化腺在C2实验中TBT积累的程度最大。在C2和C1实验中暴露的贻贝的生物浓缩因子（BCF）分别为12,100 +/- 300和2,000 +/- 10。在这项工作中使用的四个生物标记是乙酰胆碱酯酶（AChE），谷胱甘肽S-转移酶（GST），过氧化氢酶（CAT）活性和硫代巴比妥酸反应性物质（TBARS）。暴露于4-d TBT后，测得的酶活性或TBARS浓度均未观察到显着变化。

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