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首页> 外文期刊>Environmental toxicology and chemistry >Response of the amphibian tadpole Xenopus laevis to atrazine during sexual differentiation of the ovary
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Response of the amphibian tadpole Xenopus laevis to atrazine during sexual differentiation of the ovary

机译：两栖动物X爪蟾对卵巢性别分化过程中阿特拉津的反应

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Xenopus laevis tadpoles (stage 56) were exposed to 21 μg/L atrazine under laboratory-controlled conditions in a static system. Following a 48-h exposure period at 21±0.5°C during sexual differentiation, tadpoles were fixed, and the kidney-gonad complex was microdissected. Quantitative histological analysis revealed in atrazine-exposed ovaries a significant( P < 0.05) increase in frequency of secondary oogonia. Atresia, or oogonial resorption of both primary and secondary oogonia, also increased signif- icantly (P < 0.05). the results suggest that these primary germ cells, which constitute the total number of germ cells in the ovary for the reproductive life of the organism, were reduced by 20/100 following a 48-h exposure period compared to 2/100 in controls.
机译：非洲爪蟾t（第56阶段）在实验室控制的静态系统中暴露于21μg/ L阿特拉津。在性分化过程中于21±0.5°C暴露48小时后，固定t，并显微解剖肾脏-性腺复合体。定量组织学分析显示，暴露于阿特拉津的卵巢中次生卵的频率显着增加（P <0.05）。闭锁或原发性和继发性卵烟的卵黄吸收也显着增加（P <0.05）。结果表明，这些原代生殖细胞在卵巢中经过48小时的暴露后减少了20/100，而在对照组中则为2/100，而这些原代生殖细胞构成了机体生殖寿命中卵巢中生殖细胞的总数。

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