Biotic ligand model of the acute toxicity of metals. 1.techical basis

Dominic M.Di Toro; Herbert E.Allen; Harold L.Bergman

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Biotic ligand model of the acute toxicity of metals. 1.techical basis

机译：金属的急性毒性的生物配体模型。 1.技术基础

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The biotic ligand model(BLM) of acute metal toxicity to aquatic organisms is based on the idea that mortality occurs when the metal-biotic ligand complex reaches a critical concentration. For fist, the biotic ligand is either known or suspected to be the sodium or calcium channel proteins in the gill surface that regulate the ionic composition of the blood. For other organisms, it is hypothesized that a biotic ligand exists and that mortality can be modeled in a similar way. The biotic ligand interacts with the metal cations in solution. The amount of metal that binds is determined by a competition for metal ions between the biotic ligand and the other aqueous ligands, particularly dissolved organic matter(DOM), and the competition for the biotic ligand between the toxic metal ion and the other metal cations in solution, for example, calcium.

机译：急性金属对水生生物毒性的生物配体模型（BLM）是基于这样的观念，即金属-生物配体配合物达到临界浓度时会发生死亡率。首先，已知或怀疑生物配体是the表面的钠或钙通道蛋白，可调节血液的离子组成。对于其他生物，假设存在生物配体并且可以以类似方式模拟死亡率。生物配体与溶液中的金属阳离子相互作用。结合金属的量取决于生物配体与其他水性配体之间的金属离子竞争，尤其是溶解的有机物（DOM），以及有毒金属离子与其他金属阳离子之间对生物配体的竞争。溶液，例如钙。

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《Environmental toxicology and chemistry》 |2001年第10期|p.2383-2396|共14页
作者
Dominic M.Di Toro; Herbert E.Allen; Harold L.Bergman;
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作者单位

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类环境卫生、环境医学;毒物学（毒理学）;化学工业废物处理与综合利用;
关键词
Bioavailability; Metal toxicity; Metal complexation; Risk assessment;

机译：生物利用度;金属毒性;金属络合;风险评估;

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Biotic ligand model of the acute toxicity of metals. 1.techical basis

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