DIFFERENTIAL BINDING OF ENDOGENOUS STEROIDS AND CHEMICALS TO ANDROGEN RECEPTORS IN RAINBOW TROUT AND GOLDFISH

Kelly Wells; Glen Van Der Kraak

首页> 外文期刊>Environmental toxicology and chemistry >DIFFERENTIAL BINDING OF ENDOGENOUS STEROIDS AND CHEMICALS TO ANDROGEN RECEPTORS IN RAINBOW TROUT AND GOLDFISH

【24h】

DIFFERENTIAL BINDING OF ENDOGENOUS STEROIDS AND CHEMICALS TO ANDROGEN RECEPTORS IN RAINBOW TROUT AND GOLDFISH

机译：虹鳟鱼和金鱼内源性甾体与化学物质与雄激素受体的差异结合

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Androgen receptors(Ars)from fish were characterized in order to evaluate differences in the binding affinities of steroids and environmental chemicals between mammals and fish, among species of fish, and among target tissues within a species of fish. High-affinity, low-capacity Ars were identified in cytosolic fractions of raidbow trout(Oncorhynchus mykiss)and the brains, ovaries, and tests of goldfish(Carassius auratus)using ［~3H］testosterone. The binding specificities of endogenous steroids to the Ars did not differ between goldfish tissues but did differ between goolgfish and rainbow trout.

机译：为了评估哺乳动物和鱼类之间，鱼类之间以及鱼类内部目标组织之间类固醇和环境化学物质的结合亲和力的差异，对鱼类的雄激素受体（Ars）进行了表征。用［〜3H］睾丸激素可鉴定出虹鳟（Oncorhynchus mykiss）的胞浆级分，金鱼（Car鱼）的脑，卵巢和测试中的高亲和力，低容量的Ars。内源性类固醇与Ars的结合特异性在金鱼组织之间没有差异，但在墨鱼和虹鳟之间却没有差异。

著录项

来源
《Environmental toxicology and chemistry》 |2000年第8期|p.2059-2065|共7页
作者
Kelly Wells; Glen Van Der Kraak;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类环境卫生、环境医学;毒物学（毒理学）;化学工业废物处理与综合利用;
关键词
Androgen receptor; Steroid hormone; Endocrine disruption;

机译：雄激素受体类固醇激素;内分泌干扰;

相似文献

外文文献
中文文献
专利

1. Differential binding affinities of PCBs, HO-PCBs, and aroclors with recombinant human, rainbow trout (Onchorhynkiss mykiss), and green anole (Anolis carolinensis) estrogen receptors, using a semi-high throughput competitive binding assay. [J] . Matthews J, Zacharewski T Toxicological sciences: An official journal of the Society of Toxicology . 2000,第2期

机译：使用半高通量竞争性结合测定，PCBs，HO-PCBs和aroclors与重组人虹鳟（Onchorhynkiss mykiss）和绿色anole（Anolis carolinensis）雌激素受体之间的差异结合亲和力。
2. Interaction of endocrine disrupting chemicals, singly and in combination, with estrogen-, androgen-, and corticosteroid-binding sites in rainbow trout (Oncorhynchus mykiss) [J] . F. R. Knudsen, T. G. Pottinger Aquatic Toxicology . 1999,第3期

机译：虹鳟（Oncorhynchus mykiss）中内分泌干扰物单独或组合与雌激素，雄激素和皮质类固醇结合位点的相互作用
3. COMPETITIVE BINDING COMPARISON OF ENDOCRINE-DISRUPTING COMPOUNDS TO RECOMBINANT ANDROGEN RECEPTOR FROM FATHEAD MINNOW, RAINBOW TROUT, AND HUMAN [J] . Vickie S. Wilson, Mary C. Cardon, L. Earl Gray Jr., Environmental toxicology and chemistry . 2007,第9期

机译：食人鱼，虹鳟鱼和人与内分泌紊乱化合物与重组雄激素受体的竞争结合比较
4. Isolation and identification of ligands for the goldfish testicular androgen receptor in chemical recovery condensates from a Canadian bleached kraft pulp and paper mill [C] . P. Scott, C. Milestone, S. Smith, 8th International conference on fate and effects of pulp and paper mill effluents and 10th IWA symposium on forest industry wastewater 2012 . 2012

机译：从加拿大漂白牛皮纸浆和造纸厂化学回收冷凝物中分离和鉴定金鱼睾丸雄激素受体的配体
5. Regulation and expression of androgen receptor mRNA in rainbow trout at different stages of spermatogenesis. [D] . Regan, Christine Marie. 2006

机译：精子发生不同阶段虹鳟鱼雄激素受体mRNA的调控与表达
6. Biochemical studies of olfaction: isolation characterization and odorant binding activity of cilia from rainbow trout olfactory rosettes. [O] . L D Rhein, R H Cagan 1980

机译：嗅觉的生化研究：虹鳟嗅觉花丝的纤毛的分离表征和气味结合活性。
7. Interaction of endocrine disrupting chemicals, singly and in combination, with estrogen-, androgen-, and corticosteroid-binding sites in rainbow trout (Oncorhynchus mykiss) [O] . Knudsen F.R., Pottinger T.G. 1999

机译：内分泌干扰化学物质（单独和组合）与虹鳟（Oncorhynchus mykiss）中雌激素，雄激素和皮质类固醇结合位点的相互作用
8. Plasma Binding of 1-Butanol, Phenol, Nitrobenzene and Pentachlorophenol in the Rainbow Trout and Rat: A Comparative Study [R] . Schmieder, P. K., Henry, T. R. 1988

机译：虹鳟和大鼠中1-丁醇，苯酚，硝基苯和五氯苯酚的等离子体结合：对比研究

DIFFERENTIAL BINDING OF ENDOGENOUS STEROIDS AND CHEMICALS TO ANDROGEN RECEPTORS IN RAINBOW TROUT AND GOLDFISH

摘要

著录项

相似文献

相关主题

期刊订阅