POLYCHLORINATED BIPHENYLS (PCBs) DEPRESS ALLOGENEIC NATURAL CYTOTOXICITY BY EARTHWORM COELOMOCYTES

MICHAEL M. SUZUKI; EDWIN L. COOPER; GEORGE S. EYAMBE; ARTHUR J. GOVEN; LLOYD C. FITZPATRICK; BARNEY J. VENABLES

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POLYCHLORINATED BIPHENYLS (PCBs) DEPRESS ALLOGENEIC NATURAL CYTOTOXICITY BY EARTHWORM COELOMOCYTES

机译：多氯联苯（PCBs）通过土蠕菌降低了自然代谢的细胞毒性。

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Coelomocytes of the earthworm Lumbricus terrestris caused significant spontaneous allogeneic cytotoxicity in a 24-h trypan blue assay, but not in an assay using lactate dehydrogenase (LDH) release. Allogeneic cytotoxicity assays using cells from worms exposed to polychlorinated biphenyls (PCBs) suggest that PCBs can suppress a natural killing (NK-like) reaction. The implications of this work are twofold: understanding the evolution of natural killing (NK-like) activity and providing preliminary information on how spontaneous killing, a component of cellular immunity, may be compromised by pollutants.

机译：在24小时的台盼蓝试验中Lu的mb突细胞会引起明显的自发同种异体细胞毒性，但在使用乳酸脱氢酶（LDH）释放的试验中却没有。使用暴露于多氯联苯（PCBs）的蠕虫细胞进行的同种异体细胞毒性试验表明，PCBs可以抑制自然杀伤（类NK）反应。这项工作的意义是双重的：了解自然杀伤（类NK）活性的演变，并提供有关污染物如何损害自发杀伤（细胞免疫的组成部分）的初步信息。

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来源
《Environmental toxicology and chemistry》 |1995年第10期|p.1697-1700|共4页
作者
MICHAEL M. SUZUKI; EDWIN L. COOPER; GEORGE S. EYAMBE; ARTHUR J. GOVEN; LLOYD C. FITZPATRICK; BARNEY J. VENABLES;
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作者单位

Laboratory of Comparative Immunology, Department of Anatomy and Cell Biology, School of Medicine, University of California Los Angeles, Los Angeles, California 90095-1763;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类环境卫生、环境医学;毒物学（毒理学）;化学工业废物处理与综合利用;
关键词
earthworm; PCB; allogeneic; natural cytotoxicity;

机译：worm;多氯联苯;同种异体;天然细胞毒性;

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1. Can polyethylene passive samplers predict polychlorinated biphenyls (PCBs) uptake by earthworms and turnips in a biochar amended soil? [J] . Silvani Ludovica, Hjartardottir Sigurbjorg, Bielska Lucie, The Science of the Total Environment . 2019,第APRa20期

机译：聚乙烯无源采样器能否预测生物炭改良土壤中earth和萝卜吸收的多氯联苯（PCB）？
2. 1H NMR metabolomics of earthworm responses to polychlorinated biphenyl (PCB) exposure in soil [J] . Melissa L. Whitfield Åslund, André J. Simpson, Myrna J. Simpson Ecotoxicology . 2011,第4期

机译：worm对土壤中多氯联苯（PCB）暴露反应的 1 H NMR代谢组学
3. 1H NMR metabolomics of earthworm responses to polychlorinated biphenyl (PCB) exposure in soil. [J] . Whitfield Aslund ML, Simpson AJ, Simpson MJ Ecotoxicology . 2011,第4期

机译：H对土壤中多氯联苯（PCB）暴露的响应的1H NMR代谢组学。
4. Dual Microbore Column GC/HRMS Analysis of Polychlorinated Dibenzo-p-dioxins(PCDDs), Polychlorinated Dibenzofurans (PCDFs) and Dioxin-LikePolychlorinated Biphenyls (DLPCBs). [C] . K.A. MacPherson, E.J. Reiner, T.M. Kolic International symposium on halogenated environmental organic pollutants and persistent organic pollutants and POPs;DIOXIN;DIOXIN 2001;POPs . 2001

机译：多氯联苯对二恶英 r n（PCDDs），多氯联二苯并呋喃（PCDFs）和二恶英样 r n多氯联苯（DLPCB）的双微孔柱GC / HRMS分析。
5. Polychlorinated biphenyl (PCB)-induced oxidative stress mediates cytotoxicity in human breast and prostate epithelial cells [D] . Zhu, Yueming 2011

机译：多氯联苯（PCB）诱导的氧化应激介导人乳腺和前列腺上皮细胞的细胞毒性
6. POLYCHLORINATED BIPHENYL (PCB)-INDUCED OXIDATIVE STRESS AND CYTOTOXICITY CAN BE MITIGATED BY ANTIOXIDANTS FOLLOWING EXPOSURE [O] . Yueming Zhu, Amanda L. Kalen, Ling Li, -1

机译：抗氧化剂暴露后可以减轻聚氯氯联苯（PCB）诱导的氧化应激和细胞毒性
7. Can polyethylene passive samplers predict polychlorinated biphenyls (PCBs) uptake by earthworms and turnips in a biochar amended soil? [O] . Ludovica Silvani, Sigurbjörg Hjartardottir, Lucie Bielská, 2019

机译：聚乙烯无源取样器可以预测通过蚯蚓和生物炭修正的土壤中的蚯蚓和萝卜的多氯联苯（PCB）吸收吗？

POLYCHLORINATED BIPHENYLS (PCBs) DEPRESS ALLOGENEIC NATURAL CYTOTOXICITY BY EARTHWORM COELOMOCYTES

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