...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental toxicology and chemistry >Application of Bioavailability Models to Derive Chronic Guideline Values for Nickel in Freshwaters of Australia and New Zealand
【24h】

Application of Bioavailability Models to Derive Chronic Guideline Values for Nickel in Freshwaters of Australia and New Zealand

机译：生物利用率模型在澳大利亚和新西兰新水域中衍生镍的慢性指南值

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

There has been an increased emphasis on incorporating bioavailability-based approaches into freshwater guideline value derivations for metals in the Australian and New Zealand water quality guidelines. Four bioavailability models were compared: the existing European biotic ligand model (European Union BLM) and a softwater BLM, together with 2 newly developed multiple linear regressions (MLRs)-a trophic level-specific MLR and a pooled MLR. Each of the 4 models was used to normalize a nickel ecotoxicity dataset (combined tropical and temperate data) to an index condition of pH 7.5, 6 mg Ca/L, 4 mg Mg/L, (i.e., approximately 30 mg CaCO3/L hardness), and 0.5 mg DOC/L. The trophic level-specific MLR outperformed the other 3 models, with 79% of the predicted 10% effect concentration (EC10) values within a factor of 2 of the observed EC10 values. All 4 models gave similar normalized species sensitivity distributions and similar estimates of protective concentrations (PCs). Based on the index condition water chemistry proposed as the basis of the national guideline value, a protective concentration for 95% of species (PC95) of 3 mu g Ni/L was derived. This guideline value can be adjusted up and down to account for site-specific water chemistries. Predictions of PC95 values for 20 different typical water chemistries for Australia and New Zealand varied by 40-fold, which confirmed that correction for nickel bioavailability is critical for the derivation of site-specific guideline values. Environ Toxicol Chem 2020;00:1-13. (c) 2020 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
机译：有人强调将基于生物利用度的方法纳入澳大利亚和新西兰水质指南的金属淡水指南值衍生。比较了四种生物利用度模型：现有的欧洲生物配体模型（欧洲联盟BLM）和软水BLM，以及2个新开发的多元线性回归（MLRS）-A营养水平特异性MLR和汇集的MLR。 4种型号中的每一个用于将镍生态毒性数据集（组合热带和温带数据）归一化至pH 7.5,6mg Ca / L，4mg Mg / L，（即约30mg Caco3 / L硬度的指数状况）和0.5 mg doc / l。营养级别特定的MLR优于其他3种模型，其中79％的预测10％效应浓度（EC10）值在观察到的EC10值的2倍内。所有4种型号都具有类似的标准化物种敏感性分布和保护浓度（PC）的类似估计。基于指数条件水化学作为国家准则价值的基础，衍生出3μgni / l的95％（PC95）的保护浓度。该指南值可以上下调整，以考虑特定的地点水化学物质。预测澳大利亚和新西兰20种不同的典型水化学品的PC95值由> 40倍变化，这证实了镍生物利用度的校正对于衍生特定的指南值至关重要。环境毒素化学2020; 00：1-13。 （c）2020作者。 Wiley期刊LLC代表Setac的环境毒理学和化学。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号