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首页> 外文期刊>Environmental toxicology and chemistry >Life-Cycle Studies with 2 Marine Species and Bisphenol A: The Mysid Shrimp (Americamysis bahia) and Sheepshead Minnow (Cyprinodon variegatus)
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Life-Cycle Studies with 2 Marine Species and Bisphenol A: The Mysid Shrimp (Americamysis bahia) and Sheepshead Minnow (Cyprinodon variegatus)

机译：有2种海洋物种和双酚A的生命周期研究：Mysid虾（Americamysis bahia）和羊头head鱼（Cyprinodon variegatus）

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Bisphenol A (BPA) is a high production volume compound primarily used to produce epoxy resins and polycarbonate plastic. Exposure to low concentrations of BPA occurs in freshwater and marine systems, primarily from wastewater treatment plant discharges. The dataset for chronic toxicity of BPA to freshwater organisms includes studies on fish, amphibians, invertebrates, algae, and aquatic plants. To broaden the dataset, a 1.5-generation test with sheepshead minnow (Cyprinodon variegatus) and a full life-cycle test with mysid shrimp (Americamysis bahia) were conducted. Testing focused on apical endpoints of survival, growth and development, and reproduction. The respective no-observed-effect concentration (NOEC) and lowest-observed-effect concentration (LOEC) values of 170 and 370 mu g/L for mysid and 66 and 130 mu g/L for sheepshead were based on reduced fecundity. The hazardous concentrations for 5% of the species (HC5) values of 18 mu g/L were calculated from species sensitivity distributions (SSDs) with freshwater-only data and combined freshwater and marine data. Inclusion of marine data resulted in no apparent difference in SSD shape, R-2 values for the distributions, or HC5 values. Upper-bound 95th percentile concentrations of BPA measured in marine waters of North America and Europe (0.024 and 0.15 mu g/L, respectively) are below the HC5 value of 18 mu g/L. These results suggest that marine and freshwater species are of generally similar sensitivity and that chronic studies using a diverse set of species can be combined to assess the aquatic toxicity of BPA. (C) 2017 The Authors. Environmental Toxicology and Chemistry Published by Wiley Periodicals, Inc. on behalf of SETAC.
机译：双酚A（BPA）是一种高产量的化合物，主要用于生产环氧树脂和聚碳酸酯塑料。在淡水和海洋系统中暴露于低浓度的BPA，主要来自废水处理厂的排放。 BPA对淡水生物的慢性毒性数据集包括对鱼类，两栖动物，无脊椎动物，藻类和水生植物的研究。为了扩大数据集，进行了用小头min鱼（Cyprinodon variegatus）进行的1.5代测试和使用mysid虾（Americamysis bahia）的完整生命周期测试。测试的重点是生存，生长发育和繁殖的根尖。无视效果浓度（NOEC）和最低观测浓度（LOEC）值分别为：mysid为170和370μg / L，羊头为66和130μg/ L是基于繁殖力降低。根据仅含淡水的数据以及淡水和海洋数据的组合，通过物种敏感性分布（SSD）计算出5％的有害物质浓度（HC5）为18μg / L。包含海洋数据不会导致SSD形状，R-2分布值或HC5值出现明显差异。在北美和欧洲的海水中测得的BPA上限浓度为95％（分别为0.024和0.15μg / L），低于HC5值18μg/ L。这些结果表明，海洋和淡水物种通常具有相似的敏感性，并且可以结合使用多种物种的长期研究来评估BPA的水生毒性。 （C）2017作者。 Wiley Periodicals，Inc.代表SETAC发布的《环境毒理学和化学》。

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