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The seroepidemiology of varicella zoster virus among pregnant Bangladeshi and white British women in the London Borough of Tower Hamlets, UK

机译:在英国塔姆哈姆雷特市伦敦自治区的孟加拉孕妇和英国白人孕妇中,水痘带状疱疹病毒的血清流行病学

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We investigated the comparative seroepidemiology of varicella zoster virus (VZV) in pregnant women of two ethnic groups, white British and Bangladeshi, living in an inner city area of London, United Kingdom. Women aged 16-45 years were recruited from antenatal clinics of the Royal London Hospital in the Borough of Tower Hamlets. Complete data were obtained from 275 white British and 765 Bangladeshi women. VZV antibody prevalence was 93·1 % (95% CI 89·4-95·8) and 86·0% (95% CI 83·3-88·4) respectively. Women who were born in Bangladesh and lived there at least until the age of 15 years had the lowest odds of being immune (OR 0·37, 95 % CI 0·22-0·63). This implies they will have an increased risk of varicella during pregnancy. Women arriving in the United Kingdom in adulthood should be screened routinely during pregnancy and vaccination offered postpartum if they are susceptible.
机译:我们调查了居住在英国伦敦市中心两个地区的两个白人孕妇的水痘带状疱疹病毒(VZV)的比较血清流行病学。 16至45岁的妇女是从塔姆哈姆雷特自治市皇家伦敦医院的产前诊所招募的。从275名英国白人妇女和765名孟加拉妇女中获得了完整的数据。 VZV抗体患病率分别为93·1%(95%CI 89·4-95·8)和86·0%(95%CI 83·3-88·4)。在孟加拉国出生并居住到至少15岁的女性的免疫几率最低(OR 0·37,95%CI 0·22-0·63)。这意味着他们在怀孕期间水痘的风险会增加。成年到达英国的妇女应在怀孕期间进行常规筛查,如果她们容易感染,应在产后提供疫苗接种。

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