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首页> 外文期刊>Epidemiology and Infection >Emerging fluoroquinolone and macrolide resistance of Campylobactev jejuni and Campylobacter coli isolates and their serotypes in Thai children from 1991 to 2000
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Emerging fluoroquinolone and macrolide resistance of Campylobactev jejuni and Campylobacter coli isolates and their serotypes in Thai children from 1991 to 2000

机译：1991年至2000年泰国儿童空肠弯曲杆菌和弯曲杆菌分离株的氟喹诺酮和大环内酯类耐药性及其血清型

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摘要

This study investigated fluoroquinolone, macrolide resistances and serotype distributions among Campylobacter jejuni and Campylobacter coli isolated from children in Bangkok and rural settings during 1991-2000. Phenotypic identification, serotyping, and susceptibility testing were performed by standard microbiological procedures. The predominant serotypes of C. jejuni were Lior 36, 2 and 4 and of C. coli were Lior 8, 29 and 55. Resistance to nalidixic acid increased significantly during 1991-2000 and the frequency of isolates resistant to both nalidixic acid and ciprofloxacin in Bangkok was significantly greater than in rural settings. In 1996-2000, a significant trend was observed in C. jejuni isolates resistant to ciprofloxacin from Bangkok but not for macrolide resistance from both settings. In summary, fluoroquinolone resistance among C. jejuni and C. coli isolates became widespread in both Bangkok and rural settings in Thailand in the 1990s while widespread resistance to macrolides was undetected.
机译：这项研究调查了1991-2000年在曼谷和农村地区儿童中分离出的空肠弯曲杆菌和大肠弯曲杆菌中的氟喹诺酮，大环内酯类耐药性和血清型分布。通过标准微生物程序进行表型鉴定，血清分型和药敏试验。空肠弯曲杆菌的主要血清型分别为Lior 36、2和4，C。coli的主要血清型分别为Lior 8、29和55。1991年至2000年期间，对萘啶酸的抗药性显着提高，而耐萘啶酸和环丙沙星的分离株的频率在曼谷比农村地区要大得多。在1996-2000年间，在曼谷发现对空肠弯曲杆菌分离的环丙沙星具有耐药性，但在两种环境中对大环内酯类耐药均没有。总之，1990年代在泰国曼谷和泰国农村地区，空肠弯曲杆菌和大肠杆菌分离株对氟喹诺酮类药物的耐药性变得很普遍，而未发现对大环内酯类药物的广泛耐药性。

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