...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European Journal of Epidemiology >Occupational social class, risk factors and cardiovascular disease incidence in men and women: a prospective study in the European Prospective Investigation of Cancer and Nutrition in Norfolk (EPIC-Norfolk) cohort
【24h】

Occupational social class, risk factors and cardiovascular disease incidence in men and women: a prospective study in the European Prospective Investigation of Cancer and Nutrition in Norfolk (EPIC-Norfolk) cohort

机译：男性和女性的职业社会阶层，危险因素和心血管疾病的发病率：诺福克（EPIC-Norfolk）队列的欧洲癌症与营养前瞻性研究中的一项前瞻性研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objectives To investigate the association between occupational social class and cardiovascular disease (CVD) incidence, and the extent to which classical and lifestyle risk factors explain such relationships, and if any differences persist after 65 years of age. Design, Setting and Participants Prospective population study of 22,478 men and women aged 39–79 years living in the general community in Norfolk, United Kingdom, recruited using general practice age-sex registers in 1993–1997 and followed up for total mortality to 2006. Main results In both men and women an inverse relationship was observed between social class and CVD incidence, with a relative risk of social class V compared to I of 1.90 in men (95% CI 1.47 to 2.47, P < 0.001) and 1.90 in women (95% CI 1.45 to 2.49, P < 0.001). Adjusting for classical and lifestyle risk factors (age, smoking, BMI, systolic blood pressure, total blood cholesterol, history of diabetes, physical activity, weekly alcohol intake and plasma vitamin C levels) had little effect in men; the relative risk of social class V compared to I of 1.70 (95% CI 1.31 to 2.22, P < 0.001), while there was some attenuation seen in women, relative risk of social class V compared to I of 1.56 (95% CI 1.18 to 2.05, P = 0.011). The association persisted in men and women aged ≥65 years. Conclusions Some but not all of the socioeconomic differential in CVD incidence can be explained by potentially modifiable classical and lifestyle risk factors. Low social class remains a risk factor for CVD after age 65 years. Further understanding of the mechanisms underlying the association is needed if we are to reduce inequalities in health.
机译：目的探讨职业社会阶层与心血管疾病（CVD）发病率之间的关联，以及经典和生活方式危险因素在何种程度上解释这种关系，以及是否在65岁以后仍存在差异。设计，背景和参加者对1993年至1997年在英国诺福克郡普通社区生活的22,478名年龄在39-79岁的男女进行前瞻性人群研究，该研究采用普通年龄组进行招募，并随访至2006年的总死亡率。主要结果在男性和女性中，社会阶层与CVD的发生率呈反比关系，社会阶层V的相对风险与男性的I为1.90（95％CI为1.47至2.47，P <0.001）和女性为1.90 （95％CI 1.45至2.49，P <0.001）。调整经典和生活方式风险因素（年龄，吸烟，BMI，收缩压，总胆固醇，糖尿病史，身体活动，每周饮酒和血浆维生素C水平）对男性影响不大；相对于I的社会等级V的相对风险为1.70（95％CI为1.31至2.22，P <0.001），而女性则有所减弱，相对于I的社会等级V的相对风险为1.56（95％CI 1.18）至2.05，P = 0.011）。该协会坚持年龄≥65岁的男女。结论CVD发生率的部分但并非全部社会经济差异可以用可能改变的经典和生活方式危险因素来解释。较低的社会阶层仍然是65岁以后患CVD的危险因素。如果我们要减少健康方面的不平等现象，则需要进一步了解关联的潜在机制。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号