p-Chloroamphetamine (PCA) Suppresses Ingestive Behavior in Male Rats

Toru R. SAITO; Masayoshi SAITO; Toshiro ARAI

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p-Chloroamphetamine (PCA) Suppresses Ingestive Behavior in Male Rats

机译：对氯苯丙胺（PCA）抑制雄性大鼠的摄食行为。

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Ingestive behavior was activated in male rats by intraoral intake and intake from a bottle of 1-M solution of sucrose. Intraperitoneal injection of p-chloroamphetamine (PCA), releasing central 5-hydroxytryptamine (5-HT) from serotonergic nerve terminals, inhibited ingestion of the sucrose solution. Significant inhibition of sucrose intake by PCA was observed at 1.25 and 2.5 mg/kg dose in a bottle intake test, and at 5.0 mg/kg of PCA suppressed intraoral intake test.

机译：通过口服和从一瓶1M蔗糖溶液中摄入，可以激活雄性大鼠的食性。腹膜内注射对氯苯丙胺（PCA），从血清素能神经末梢释放中心5-羟色胺（5-HT），抑制了蔗糖溶液的摄入。在瓶摄入测试中以1.25和2.5 mg / kg剂量观察到PCA对蔗糖摄入的显着抑制，而在5.0 mg / kg PCA抑制的口腔内摄入测试中观察到PCA显着抑制蔗糖摄入。

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来源
《Experimental Animals》 |1999年第4期|p.263-267|共5页
作者
Toru R. SAITO; Masayoshi SAITO; Toshiro ARAI;
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作者单位

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类动物学;
关键词
appetitive and consummatory ingestive behavior; intraoral intake and intake; from a bottle;

机译：食欲旺盛的消化行为;口内摄入量和摄入量;从瓶子里;

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2. Dopamine D(2) receptors and ingestive behavior: brainstem mediates inhibition of intraoral intake and accumbens mediates aversive taste behavior in male rats. [J] . Sederholm F, Johnson AE, Brodin U, Psychopharmacology . 2002,第2期

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4. Design of a instrumentation module for monitoring ingestive behavior in laboratory studies [C] . Fontana Juan M., Lopez-Meyer Paulo, Sazonov Edward S. 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2011

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6. Social buffering suppresses fear-associated activation of the lateral amygdala in male rats: behavioral and neurophysiological evidence [O] . Felipe Fuzzo, Jumpei Matsumoto, Yasushi Kiyokawa, 2015

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7. p-Chloroamphetamine(PCA) Suppresses Ingestive Behavior in Male Rats. [O] . Toru R. SAITO, Masayoshi SAITO, Toshiro ARAI, 1999

机译：对氯邻胺（PCA）抑制雄性大鼠的摄入行为。

p-Chloroamphetamine (PCA) Suppresses Ingestive Behavior in Male Rats

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