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Effect of P. frutescens var administration in hypertensionai experimental Dahl rat

机译：苦参粉对高血压实验性Dahl大鼠的影响

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α - linolenic acid is essential fatty acid metabolized in the body DHA, EPA. In addition, it is expected when there is an effect in the food which includes a lot thing for diseases such as hypertension, cancer, arterial sclerosis, cerebral infarction in human. Because we let you add the black sesame which does not include P. frutescens var (PSE) including a lot of α - linolenic acids, a αα - linolenic acid almost in composition feed AIN-93G this time and reviewed effect of Dahl rat, we report it. Method: We divided 18 males 6 weeks of age Dahl rats into three groups after breeding preliminarily for one week. The feed let we made 6% PFE addition feed, 6% BSE addition feed as basal diet and take composition feed (AIN-93G) made in Oriental yeast company with purified water ad libitum. Blood pressure measured it to 11 weeks of age than seven week of age at the time of an experiment start of age and observed the blood pressure change. Results and consideration: Significant difference of 1% and 5% was found in the Dahl rat between AIN group and 6% BSE group of systolic blood pressure value in 11 weeks. When we put LDH and total cholesterol, 1% and significant difference of 5% were found between AIN group and 6% PFE group. It revealed glomerular atrophy and alteration in kidney histologically and was able to observe hyalinization tubular partly, but the specific alteration in each group was absent. Aberration was not present in liver, aorta descendens. We confirmed Anti-cholesterol action from an experiment this time. However, more detailed want to review myocardial protection of PSE and these terrorism - roux degradation action in future. Dahl rat has presented hypertension in the results that we used this composition for and wants to evaluate it as a useful model animal of hypertensionai mechanism.
机译：α-亚麻酸是人体DHA，EPA中代谢的必需脂肪酸。另外，期望在对人类的高血压，癌症，动脉硬化，脑梗塞等疾病有很多影响的食品中起作用。因为这次让您添加成分饲料AIN-93G中几乎不含α-亚麻酸，几乎不含α-亚麻酸的黑芝麻（PSE），所以回顾了达尔大鼠的作用，报告它。方法：我们将初步繁殖1周的18只雄性6周龄Dahl大鼠分为三组。饲料以基础饲料为基准，分别添加了6％PFE饲料，6％BSE饲料，并随意摄取了东方酵母公司制造的组合饲料（AIN-93G）。在实验年龄开始时，血压测量到比7周龄大11周龄，并观察到血压变化。结果与考虑：11周内，AIN组和6％BSE组的Dahl大鼠收缩压值有1％和5％的显着差异。当我们将LDH和总胆固醇相加时，AIN组和6％PFE组之间的差异为1％和5％。它在组织学上显示出肾小球萎缩和肾脏改变，并且能够部分观察到透明化肾小管，但是每组中都没有特定的改变。肝脏，主动脉下降均未出现畸变。这次我们通过实验确认了抗胆固醇的作用。但是，更详细的内容是想回顾一下PSE的心肌保护作用以及这些恐怖主义-助剂将来的降解作用。达尔大鼠已在我们使用该组合物的结果中表现出高血压，并希望将其评估为有用的高血压机制模型动物。

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