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The Clinical Analysis of Endogenous Endophthalmitis

机译：内源性眼内炎的临床分析

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Purpose: To study the clinical characteristics, therapeutic efficacy and investigate prognostic factors of endogenous endophthalmitis. Methods: Twenty-eight cases (28 eyes) of endogenous endophthalmitis were surveyed retrospectively. The clinical characteristics, primary infection foci, predisposing systemic disease, complications, pathogens examination, therapeutic options and efficacy were analysed. Results: The endogenous endophthalmitis occurred more frequently in the right eye than in the left one. The respiratory tract was the most common primary foci. The positive rate of pathogens culture was higher in vitreous sample than that in other tissues. Cataract and retinal detachment were the common complications. The visual improvement and infection control were achieved in 13 eyes (46.43%). These 13 patients received treatment (3.77+-2.49)days after onset of endophthalmitis being much earlier than that of others [(10.13+-4.98)days, P=0.002]. The prognosis was relevant to the type of the disease. The anterior segment inflammation type (anterior type) had better prognosis than posterior segment inflammation type (posterior type) and that of inflammation in both parts (mix type) (P < 0.05). There were no significant relation between the prognosis and the age, predisposing systemic disease, vitreous antibiotic injection and vitrectomy (P> 0.05). Conclusions: Endogenous endophthalmitis is a vital ocular emergency. Early diagnosis and effective treatment combination with systemic and local antibiotics are of significant value. The anterior type is prone to have better outcome than the others.
机译：目的：研究内源性眼内炎的临床特点，治疗效果及预后因素。方法：回顾性调查28例28眼内源性眼内炎。分析了临床特征，原发感染灶，易感性全身疾病，并发症，病原体检查，治疗选择和疗效。结果：内源性眼内炎在左眼发生的频率比左眼发生的频率高。呼吸道是最常见的原发灶。玻璃体样本中病原体培养的阳性率高于其他组织。白内障和视网膜脱离是常见的并发症。 13只眼（46.43％）实现了视觉改善和感染控制。这13例患者在眼内炎发作后（3.77 + -2.49）天接受治疗，比其他人早得多[（10.13 + -4.98）天，P = 0.002]。预后与疾病类型有关。前节发炎型（前发型）的预后要好于后节发炎型（后发型）和两个部位的发炎（混合型）（P <0.05）。预后与年龄，易感性全身疾病，玻璃体抗生素注射和玻璃体切除术之间无显着相关性（P> 0.05）。结论：内源性眼内炎是紧急的眼科急诊。早期诊断和有效治疗结合全身和局部抗生素具有重要价值。前者比其他人更容易获得更好的结果。

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