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首页> 外文期刊>Food Chemistry >Chemistry, oxidative stability and bioactivity of oil extracted from Rosa rugosa (Thunb.) seeds by supercritical carbon dioxide
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Chemistry, oxidative stability and bioactivity of oil extracted from Rosa rugosa (Thunb.) seeds by supercritical carbon dioxide

机译：通过超临界二氧化碳从Rosa Rugosa（Thunb.）种子提取的油化学，氧化稳定性和生物活性

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摘要

Rosa rugosa Thunb. seed oil (RR) extracted by supercritical CO2 was investigated. RR chemical composition, radical scavenging effect and oxidative stability were evaluated. RR aqueous emulsions were examined for cell cytotoxicity, proliferation, redox state and migration using mouse embryonic fibroblast Balb/3T3, human dermal fibroblast NHDF cell lines, and on neoplastic cell lines: acute monocytic leukemia THP-1 and lung adenocarcinoma A549. RR total contents of phytosterols, tocopherols, carotenoids and phenolics were 10115.23, 784.16, 40.32 and 10.30 mg/kg, respectively. Rich antioxidant composition of RR was reflected in its high antioxidant activity (2.1 mM/kg Trolox equivalent) as well as oxidative stability (activation energy 105.6 kJ/mol). The RR emulsions led to marked augmentation of the total cell protein content in BALB/3T3 and NHDF cultures, inhibited cancer cell migration and reduced ROS formation. The studied RR oil proved to have a remarkable combination of bioactive compounds and to exert an antioxidative and chemopreventive effects.
机译：Rosa Rugosa Thunb。研究了超临界CO2提取的种子油（RR）。评估RR化学成分，自由基清除效果和氧化稳定性。使用小鼠胚胎成纤维细胞BALB / 3T3，人皮肤成纤维细胞NHDF细胞系和肿瘤细胞系中的细胞细胞毒性，增殖，氧化还原状态和迁移进行RR含水乳液：急性单核细胞系THP-1和肺腺癌A549。植物甾醇，生育酚，类胡萝卜素和酚类的全部含量分别为10115.23,784.16,40.32和10.30 mg / kg。 RR的富抗氧化剂组合物反映在其高抗氧化活性（2.1mm / kg拖车等当量）以及氧化稳定性（活化能量105.6kJ / mol）中。 RR乳液导致BALB / 3T3和NHDF培养中的总细胞蛋白质含量的增强，抑制癌细胞迁移和降低的ROS形成。所研究的RR油证明具有卓越的生物活性化合物组合并施加抗氧化和化学预防效果。

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  • 来源
    《Food Chemistry》 |2021年第15期|127649.1-127649.9|共9页
  • 作者

    Grajzer Magdalena; Wiatrak Benita; Gebarowski Tomasz; Matkowski Adam; Grajeta Halina; Roj Edward; Kulma Anna; Prescha Anna;

  • 作者单位

    Wroclaw Med Univ Dept Food Sci & Dietet Borowska 211 PL-50556 Wroclaw Poland;

    Wroclaw Med Univ Dept Basic Med Sci Borowska 211 PL-50556 Wroclaw Poland;

    Wroclaw Med Univ Dept Basic Med Sci Borowska 211 PL-50556 Wroclaw Poland;

    Wroclaw Med Univ Dept Pharmaceut Biol & Bot Bot Garden Med Plants Jana Kochanowskiego 14 PL-51506 Wroclaw Poland;

    Wroclaw Med Univ Dept Food Sci & Dietet Borowska 211 PL-50556 Wroclaw Poland;

    New Chem Synth Inst Supercrit Extract Dept Al Tysiaclecia Panstwa Polskiego 13a PL-24110 Pulawy Poland;

    Univ Wroclaw Dept Genet Biochem Przybyszewskiego 63-77 PL-51148 Wroclaw Poland;

    Wroclaw Med Univ Dept Food Sci & Dietet Borowska 211 PL-50556 Wroclaw Poland;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Rosa rugosa oil; Supercritical carbon dioxide extraction; Antioxidants; Oxidative stability; Fibroblast cell lines; Cancer cells;

    机译：Rosa Rugosa油;超临界二氧化碳提取;抗氧化剂;氧化稳定性;成纤维细胞系;癌细胞;

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