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首页> 外文期刊>Lebensmittelchemie >Pyrrolizidine alkaloids in honey on the Ghanaian market: A potential health risk to honey consumers
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Pyrrolizidine alkaloids in honey on the Ghanaian market: A potential health risk to honey consumers

机译：加纳市场蜂蜜中的吡咯烷定生物碱：蜂蜜消费者可能面临健康风险

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摘要

In Ghana, honey is used as a sweetener in beverages and in herbal medicines due to its health benefits. However, honeys are prone to contamination with hepatotoxic pyrrolizidine alkaloids (PAs) from bees foraging on PA-containing plants. This paper deals with the quantification of PAs in honey em-anating from different Ghanaian markets, geographical and botanical origins in order to assess its potential health threat. PAs of 48 honey samples were extracted with 0.05 M sulph-uric acid and then purified and analysed by Strata SCX-SPE and HPLC-ESI-MS/MS sum parameter method, respec-tively. The results show that a total of 88 % of the raw honeys sold in the various markets were PA positive including all honeys from the supermarkets. The highest concentration of PAs (2638.7 μg/kg) was found in a honey from Hoezo; a town in the rain forest area of the Volta region. The mean PA concentration of the positive samples was 323.1 μg/kg. Generally, higher concentrations of PAs were observed in light amber and forest honeys, while lower amounts were detected in extra light amber and savanna honeys. The determined PA pattern in the honeys could assist beekeepers in selecting the most suitable locations for the production of honey low in PA. Furthermore, the geographically central location of Ghana within West Africa can serve as a model to study PA contamination in honeys in the sub-region. PA concentrations of Ghanaian honey were generally above the tolerable levels of exposure (0.007 μg/kg/day and 0.1 μg/kg bw/day)proposed by some regulatory agencies thereby posing food safety concerns for local honey consumers and export-ing destinations.
机译：在加纳，蜂蜜具有健康益处，因此可在饮料和草药中用作甜味剂。但是，蜜蜂在含有PA的植物上觅食时，容易被蜂蜜中的肝毒性吡咯烷啶生物碱（PAs）污染。本文对来自加纳不同市场，地理和植物来源的蜂蜜中的PA进行定量分析，以评估其对健康的潜在威胁。用0.05 M的硫酸提取48个蜂蜜样品的PA，然后分别通过Strata SCX-SPE和HPLC-ESI-MS / MS和参数方法进行纯化和分析。结果表明，在各个市场上出售的原始蜂蜜中，有88％为PA阳性，包括来自超市的所有蜂蜜。在Hoezo的蜂蜜中发现最高的PAs浓度（2638.7μg/ kg）。沃尔特地区雨林地区的一个城镇。阳性样品的平均PA浓度为323.1μg/ kg。通常，在淡琥珀色和森林蜂蜜中观察到较高的PA含量，而在淡淡琥珀色和热带稀树草原蜂蜜中发现的含量较低。蜂蜜中确定的PA模式可以帮助养蜂人选择最合适的位置生产低PA的蜂蜜。此外，加纳在西非的地理中心位置可作为研究该次区域蜂蜜中PA污染的模型。加纳蜂蜜的PA浓度通常高于一些监管机构建议的可承受的暴露水平（0.007μg/ kg /天和0.1μg/ kg bw /天），从而给当地蜂蜜消费者和出口目的地带来食品安全问题。

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  • 来源
    《Lebensmittelchemie》 |2016年第3期|54-54|共1页
  • 作者

    E. Letsyo; G. Jerz; P. Winterhalter; T. Beuerle;

  • 作者单位

    Institut für Lebensmittelchemie, Technische Universität Braunschweig;

    Institut für Lebensmittelchemie, Technische Universität Braunschweig;

    Institut für Lebensmittelchemie, Technische Universität Braunschweig;

    Institut für Pharmazeutische Biologie, Technische Universität Braunschweig;

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