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首页> 外文期刊>Deutsche Zeitschrift fur Sportmedisin >Aerobes Ausdauertraining am Morgen als Therapie gegen Winterdepression
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Aerobes Ausdauertraining am Morgen als Therapie gegen Winterdepression

机译：早晨进行有氧耐力训练，以治疗冬季抑郁症

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Winter depression (SAD) is thought to be a consequence of phase disturbances in the circadian timing system. Corresponding to this phase-shift hypothesis exposure to bright light in the morning has been proved to be an effective therapy for SAD. Since in a diurnal primate induced motor activity was shown to produce similar phase responses as light does, we tested whether early morning exercises also have a therapeutic effect on SAD. Each 12 winter-depressed and healthy women (experimental group EXP, control group CⅠ) experienced early morning exercises in form of aerobics on 12 successive days from 07:00- 08:00. A second control group (CⅡ) of 9 winter-depressed women came together at the same time of day without performing exercises. Before and after the test period depression scores were determined by the Hamilton Depression Rating Scale and Beck's Depression Inventory. Part of EXP (n = 9) and Cl (n = 11) experienced 28-h constant routines with blood sampling at 1 h or 2 h intervals. Plasma samples were analysed for hormone (melatonin, prolactin, cortisol, TSH, T3J4) and neurotransmitter (serotonin, do-pamine, NE, HVA, 5-HIAA) concentrations. After treatment depression scores were significantly reduced in EXP (p < 0.01) and remained unchanged in CⅡ. In EXP plasma levels (24 h-means) of melatonin and free T4 (p < 0.01) as well as T4 and free T3 (p < 0.05) were decreased whereas the dopamine level was increased (p < 0.05). In Cl reduced levels of cortisof, 5HIAA (p < 0.01), T4, T3 and free T3 (p < 0.05) were observed. The melatonin rhythm was phase advanced in EXP and CⅠ (p < 0.05) after the exercise period while the 24 h-patterns of cortisol, prolactin, and dopamine were advanced only in Cl. Thus early morning exercises may represent a suitable alternative to the light therapy of SAD. The observed improvement in mood and the phase advance of the melatonin rhythm are in keeping with Lewy's phase- shift hypothesis.
机译：人们认为冬季抑郁症（SAD）是昼夜节律系统中相位干扰的结果。与这种相移假说相对应的是，早晨将其暴露在强光下是一种有效的SAD治疗方法。由于在昼夜灵长类动物中诱导的运动活动显示出与光相似的相位响应，因此我们测试了清晨锻炼是否也对SAD有治疗作用。每12名冬季抑郁和健康的女性（实验组EXP，对照组CⅠ）在07:00至08:00连续12天进行有氧运动形式的清晨锻炼。第二个对照组（CⅡ）由9名冬季抑郁妇女组成，他们在一天的同一时间不做运动而聚在一起。在测试期间之前和之后，抑郁评分由汉密尔顿抑郁量表和贝克抑郁量表确定。 EXP（n = 9）和Cl（n = 11）的一部分经历了28小时的固定程序，每隔1 h或2 h进行一次血液采样。分析血浆样品中的激素（褪黑激素，催乳素，皮质醇，TSH，T3J4）和神经递质（血清素，多巴胺，NE，HVA，5-HIAA）浓度。治疗后，抑郁指数的EXP显着降低（p <0.01），而CⅡ则保持不变。在EXP中，褪黑激素和游离T4（p <0.01）以及T4和游离T3（p <0.05）的血浆水平（24 h均值）降低，而多巴胺水平升高（p <0.05）。在Cl中可的松水平降低，观察到5HIAA（p ＜0.01），T4，T3和游离T3（p ＜0.05）。运动后，EXP和CⅠ中的褪黑激素节律提前（p <0.05），而皮质醇，催乳素和多巴胺的24 h模式仅在Cl中进展。因此，清晨锻炼可能是SAD光疗的合适替代方法。观察到的情绪改善和褪黑激素节律的相移符合路易的相移假说。

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