Immune System of Russian Cosmonauts after Orbital Space Flights

M. P. Rykova

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Immune System of Russian Cosmonauts after Orbital Space Flights

机译：俄罗斯宇航员在轨道太空飞行后的免疫系统

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This article is an overview of the results of studies of the immune systems of cosmonauts. The use of a systematic approach to evaluating various components of the immune system made it possible to identify a number of characteristics of adaptive change, including the quantitative and functional changes of the innate and adaptive immunity. The most important ones are the changes in the system of signaling pattern recognition receptors (Toll-like receptors, TLRs), which manifest themselves as a decrease in the content and cytokine-producing ability of monocytes and granulocytes expressing TLR2, TLR4, and TLR6, as well as in the suppression of the functional potential of natural killer (NK)- and T-cell components of adaptive immunity and are discussed.

机译：本文概述了宇航员免疫系统的研究结果。通过使用系统性方法评估免疫系统的各个组成部分，可以识别出适应性变化的许多特征，包括先天性和适应性免疫的数量和功能变化。最重要的是信号模式识别受体（Toll样受体，TLR）系统的变化，这表现为表达TLR2，TLR4和TLR6的单核细胞和粒细胞的含量和细胞因子生成能力的降低，以及在抑制天然杀伤（NK）和T细胞成分的适应性免疫功能潜力方面进行了讨论。

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来源
《Human physiology》 |2013年第5期|557-566|共10页
作者
M. P. Rykova;
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作者单位

Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, 123007 Russia;

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原文格式 PDF
正文语种 eng
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关键词
space flight; innate immunity; adaptive immunity; adaptation;

机译：航天;先天免疫;适应性免疫适应;

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专利

1. Tolerance of G-Loads by a Russian Cosmonaut and a NASA Astronaut during the Soyuz Space Vehicle De-Orbit after a 340-Day Mission to the International Space Station [J] . A. R. Kotovskaya, M. I. Koloteva, T. M. Glebova Human physiology . 2019,第7期

机译：俄罗斯宇航员和美国宇航局宇航员在塞摩斯空间车辆在国际空间站的340天任务后，俄罗斯宇航员和美国宇航局宇航员的耐受性
2. Parameters of the Innate and Adaptive Immunity in Cosmonauts after Long-Term Space Flight on Board the International Space Station [J] . B. V. Morukov, M. P. Rykova, E. N. Antropova, Human physiology . 2010,第3期

机译：国际空间站长期太空飞行后宇航员的先天性和适应性免疫参数
3. T-cell immunity and cytokine production in cosmonauts after long-duration space flights [J] . B. Morukov, M. Rykova, E. Antropova, Acta astronautica . 2011,第7a8期

机译：长期太空飞行后宇航员的T细胞免疫和细胞因子产生
4. Dynamics of aquaporin-3 content in erythrocytes of the Russian cosmonauts during long-term space flights on the Russian segment of the International Space Station [C] . I.A. Nichiporuk, G.Yu. Vassilieva International astronautical congress . 2016

机译：在国际空间站俄罗斯段进行的长期太空飞行中，俄罗斯宇航员的红细胞中Aquaporin-3含量的动态
5. Marginal regions in discursive space: An examination of socio-economic conditions, development paths and spatial differentiation in the economic systems of the Canadian and Russian North [D] . Petrov, Andrey N. 2008

机译：话语空间中的边缘区域：对加拿大和俄罗斯北部经济体系的社会经济条件，发展路径和空间差异的考察
6. Publisher Correction: Protein expression changes caused by spaceflight as measured for 18 Russian cosmonauts [O] . Irina M. Larina, Andrew J. Percy, Juncong Yang, -1

机译：出版商更正：太空飞行引起的蛋白质表达变化针对18位俄罗斯宇航员进行了测量
7. A Historical Look at the Biomedical Tests Conducted by Cosmonauts during the Orbital Flight Soyuz 30 / Salyut 6 [O] . Krzysztof Klukowski, Franciszek Skibniewski 2013

机译：历史看看宇航员在轨道飞行中进行的生物医学试验Soyuz 30 / Salyut 6
8. The Dynamics of Blood Circulation Parameters of the Cerebral Vascular System During Longitudinal Gravitational Loads; Emotional Stress of Cosmonauts During Space Flights; a Symposium on Applied Microbiology (In Stockholm) [R] . Moskalenko, Y. E., Gazenko, O. G., Yazdovskii, V. I., 1964

机译：纵向重力荷载作用下脑血管系统血液循环参数的动态变化;太空飞行中宇航员的情绪压力;应用微生物学研讨会（斯德哥尔摩）

Immune System of Russian Cosmonauts after Orbital Space Flights

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