...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Human physiology >Changes in Bioenergetic Functions and Performance Capacity of Athletes after Administration of a Polyphenolic Antihypoxic Agent
【24h】

Changes in Bioenergetic Functions and Performance Capacity of Athletes after Administration of a Polyphenolic Antihypoxic Agent

机译：服用多酚抗氧剂后运动员生物能功能和运动能力的变化

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A study was made of the effects of a polyphenolic antihypoxic agent on respiration in isolated mitochondria and homogenates of skeletal muscles and on the bioenergetic functions and performance capacity of runners. Polarographic analysis showed that preincubation of mitochondria isolated from skeletal muscles with the antihypoxic agent inhibited glutamate oxidation more than twofold in state 4. In homogenates of skeletal muscles, the antihypoxic agent in the presence or absence of an uncoupler strongly inhibited or slightly stimulated glutamate oxidation in the initial mitochondrial state, respectively. Thus, the antihypoxic agent inhibited mitochondrial ATPase but did not change the ATP synthase activity or exert a direct effect on the respiratory chain. The antihypoxic agent administered to runners at a concentration of about 30 mg/kg body mass 1 h prior to exercise at maximum power with a maximum duration of 1-10 min allowed higher acidification but did not affect the major bioenergetic functions such as O_2 consumption, excess CO_2 production, O_2 debt, and O_2 demand. The agent substantially increased the performance capacity of runners during exercise with a maximum duration of 3-10 min. Under competition conditions, administration of the agent to runners improved the results by 2-6% in 200- to 10000-m races.
机译：研究了多酚抗氧剂对孤立的线粒体和骨骼肌匀浆的呼吸作用以及对跑步者的生物能功能和运动能力的影响。极谱分析显示，在状态4下，从骨骼肌分离的线粒体与抗氧剂的预孵育抑制了谷氨酸的氧化两倍以上。初始线粒体状态。因此，该抗氧剂抑制线粒体ATP酶，但不改变ATP合酶活性或对呼吸链没有直接作用。在以最大力量进行运动前1小时以大约30 mg / kg体重的浓度向跑步者服用抗氧剂，最大持续时间为1-10分钟，可以使酸度更高，但不会影响主要的生物能功能，例如消耗O_2，多余的CO_2产量，O_2债务和O_2需求。该试剂可显着提高跑步者在运动中的表现能力，最长持续时间为3-10分钟。在比赛条件下，在200至10000 m的比赛中，对跑步者进行管理可将结果提高2-6％。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号