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Brain Modulyzer: Interactive Visual Analysis of Functional Brain Connectivity

机译:Brain Modulyzer:功能性大脑连通性的交互式视觉分析

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摘要

We present Brain Modulyzer, an interactive visual exploration tool for functional magnetic resonance imaging (fMRI) brain scans, aimed at analyzing the correlation between different brain regions when resting or when performing mental tasks. Brain Modulyzer combines multiple coordinated views—such as heat maps, node link diagrams, and anatomical views—using brushing and linking to provide an anatomical context for brain connectivity data. Integrating methods from graph theory and analysis, e.g., community detection and derived graph measures, makes it possible to explore the modular and hierarchical organization of functional brain networks. Providing immediate feedback by displaying analysis results instantaneously while changing parameters gives neuroscientists a powerful means to comprehend complex brain structure more effectively and efficiently and supports forming hypotheses that can then be validated via statistical analysis. To demonstrate the utility of our tool, we present two case studies—exploring progressive supranuclear palsy, as well as memory encoding and retrieval.
机译:我们介绍了Brain Modulyzer,这是一种用于功能磁共振成像(fMRI)脑部扫描的交互式视觉探索工具,旨在分析静止或执行精神任务时不同脑区之间的相关性。 Brain Modulyzer结合了多种协调的视图(例如热图,节点链接图和解剖视图),并使用了笔刷和链接功能来提供大脑连接数据的解剖上下文。来自图论和分析的集成方法(例如社区检测和派生图度量)使探索功能性大脑网络的模块化和分层组织成为可能。通过在更改参数的同时即时显示分析结果来提供即时反馈,为神经科学家提供了一种强大的手段,可以更有效,更有效地理解复杂的大脑结构,并支持形成可以通过统计分析进行验证的假设。为了演示我们工具的实用性,我们提供了两个案例研究-探索进行性核上性麻痹以及记忆编码和检索。

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